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Osimertinib and Capmatinib Combination Therapy to Overcome MET Y1003N-Mediated Resistance in EGFR-Mutant NSCLC: A Case Report

Osimertinib, a third-generation EGFR tyrosine kinase inhibitor, is the frontline standard in the treatment of metastatic EGFR-mutant NSCLC. Although osimertinib is effective, disease progression occurs in virtually all patients, mediated by a heterogeneous array of resistance mechanisms. Activation...

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Detalles Bibliográficos
Autores principales:	Wilgucki, Molly, Yeung, Vincent, Ho, Grace, Bravo Montenegro, Gabriela L., Jones, Greg, Reuss, Joshua E., Liu, Stephen V., Kim, Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516460/ https://www.ncbi.nlm.nih.gov/pubmed/36188633 http://dx.doi.org/10.1016/j.jtocrr.2022.100396

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