Rational use of antibiotics in children with diabetic ketoacidosis needs attention

Diabetic ketoacidosis (DKA) in children may lead to acute kidney injury (AKI). Among 45 children with DKA in our center, eight cases had AKI on admission, and in one child, his kidney function did not recover until 3 mo after discharge. This child was treated with antibiotics (cephalosporin), and we...

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Detalles Bibliográficos
Autor principal: Wang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Field of Vision
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516495/
https://www.ncbi.nlm.nih.gov/pubmed/36185097
http://dx.doi.org/10.5409/wjcp.v11.i5.405
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author Wang, Xu
author_facet Wang, Xu
author_sort Wang, Xu
collection PubMed
description Diabetic ketoacidosis (DKA) in children may lead to acute kidney injury (AKI). Among 45 children with DKA in our center, eight cases had AKI on admission, and in one child, his kidney function did not recover until 3 mo after discharge. This child was treated with antibiotics (cephalosporin), and we cannot rule out delayed AKI recovery due to the combined effects of the drug and the disease. Pediatricians should be concerned about the impact of nephrotoxic drug and disease interactions on children's kidney function, and need to follow up children with DKA and AKI to determine the development of AKI.
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spelling pubmed-95164952022-09-29 Rational use of antibiotics in children with diabetic ketoacidosis needs attention Wang, Xu World J Clin Pediatr Field of Vision Diabetic ketoacidosis (DKA) in children may lead to acute kidney injury (AKI). Among 45 children with DKA in our center, eight cases had AKI on admission, and in one child, his kidney function did not recover until 3 mo after discharge. This child was treated with antibiotics (cephalosporin), and we cannot rule out delayed AKI recovery due to the combined effects of the drug and the disease. Pediatricians should be concerned about the impact of nephrotoxic drug and disease interactions on children's kidney function, and need to follow up children with DKA and AKI to determine the development of AKI. Baishideng Publishing Group Inc 2022-09-09 /pmc/articles/PMC9516495/ /pubmed/36185097 http://dx.doi.org/10.5409/wjcp.v11.i5.405 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Field of Vision
Wang, Xu
Rational use of antibiotics in children with diabetic ketoacidosis needs attention
title Rational use of antibiotics in children with diabetic ketoacidosis needs attention
title_full Rational use of antibiotics in children with diabetic ketoacidosis needs attention
title_fullStr Rational use of antibiotics in children with diabetic ketoacidosis needs attention
title_full_unstemmed Rational use of antibiotics in children with diabetic ketoacidosis needs attention
title_short Rational use of antibiotics in children with diabetic ketoacidosis needs attention
title_sort rational use of antibiotics in children with diabetic ketoacidosis needs attention
topic Field of Vision
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516495/
https://www.ncbi.nlm.nih.gov/pubmed/36185097
http://dx.doi.org/10.5409/wjcp.v11.i5.405
work_keys_str_mv AT wangxu rationaluseofantibioticsinchildrenwithdiabeticketoacidosisneedsattention

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