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The DNA repair function of BCL11A suppresses senescence and promotes continued proliferation of triple-negative breast cancer cells

We identified the BCL11A protein in a proximity-dependent biotinylation screen performed with the DNA glycosylase NTHL1. In vitro, DNA repair assays demonstrate that both BCL11A and a small recombinant BCL11A(160–520) protein that is devoid of DNA binding and transcription regulatory domains can sti...

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Detalles Bibliográficos
Autores principales:	Vickridge, Elise, Faraco, Camila C F, Tehrani, Payman S, Ramdzan, Zubaidah M, Djerir, Billel, Rahimian, Hedyeh, Leduy, Lam, Maréchal, Alexandre, Gingras, Anne-Claude, Nepveu, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	DNA Damage Sensing and Repair
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516615/ https://www.ncbi.nlm.nih.gov/pubmed/36186110 http://dx.doi.org/10.1093/narcan/zcac028

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