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Alcohol promotes epithelial mesenchymal transformation-mediated premetastatic niche formation of colorectal cancer by activating interaction between laminin-γ2 and integrin-β1

BACKGROUND: Colorectal cancer (CRC) is a common malignant tumor. Alcohol consumption is positively correlated with CRC malignant metastasis; however, the mechanism is unclear. The interaction between laminin-γ2 (LAMC2) and integrin-β1 (ITGB1) plays a role in premetastatic niche signaling, which may...

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Detalles Bibliográficos
Autores principales:	Nong, Fei-Fei, Liang, Yu-Qi, Xing, Shang-Ping, Xiao, Yin-Fang, Chen, Hui-Hui, Wen, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2022
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516679/ https://www.ncbi.nlm.nih.gov/pubmed/36188720 http://dx.doi.org/10.3748/wjg.v28.i35.5154

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