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METTL3 suppresses anlotinib sensitivity by regulating m(6)A modification of FGFR3 in oral squamous cell carcinoma

BACKGROUND: N6-methyladenosine (m(6)A) is an abundant nucleotide modification in mRNA, but there were few studies on its role in cancer drug sensitivity and resistance. Anlotinib has been proved to have effective antitumor effects in oral squamous cell carcinoma (OSCC) in our previous study. Here, w...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Li, Shuai, Huang, Zhexun, Cao, Congyuan, Wang, Anxun, He, Qianting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516809/
https://www.ncbi.nlm.nih.gov/pubmed/36167542
http://dx.doi.org/10.1186/s12935-022-02715-7