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Risk stratification and pathway analysis based on graph neural network and interpretable algorithm

BACKGROUND: Pathway-based analysis of transcriptomic data has shown greater stability and better performance than traditional gene-based analysis. Until now, some pathway-based deep learning models have been developed for bioinformatic analysis, but these models have not fully considered the topolog...

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Detalles Bibliográficos
Autores principales: Liang, Bilin, Gong, Haifan, Lu, Lu, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516820/
https://www.ncbi.nlm.nih.gov/pubmed/36167504
http://dx.doi.org/10.1186/s12859-022-04950-1