In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury

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The hallmark of severe COVID-19 involves systemic cytokine storm and multi-organ failure including testicular injury and germ cell depletion. The ACE2 receptor is also expressed in the resident testicular cells however, SARS-CoV-2 infection and mechanisms of testicular injury are not fully understoo...

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Detalles Bibliográficos
Autores principales: Giannakopoulos, Stefanos, Strange, Daniel P, Jiyarom, Boonyanudh, Abdelaal, Omar, Bradshaw, Aaron W, Nerurkar, Vivek R, Ward, Monika A, Bakse, Jackson, Yap, Jonathan, Vanapruks, Selena, Boisvert, William, Tallquist, Michelle D, Shikuma, Cecilia, Sadri-Ardekani, Hooman, Clapp, Philip, Murphy, Sean, Verma, Saguna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516847/
https://www.ncbi.nlm.nih.gov/pubmed/36172118
http://dx.doi.org/10.1101/2022.09.21.508904
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