Generation and functional analysis of defective viral genomes during SARS-CoV-2 infection

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Defective viral genomes (DVGs) have been identified in many RNA viruses as a major factor influencing antiviral immune response and viral pathogenesis. However, the generation and function of DVGs in SARS-CoV-2 infection are less known. In this study, we elucidated DVG generation in SARS-CoV-2 and i...

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Detalles Bibliográficos
Autores principales: Zhou, Terry, Gilliam, Nora J., Li, Sizhen, Spaudau, Simone, Osborn, Raven M., Anderson, Christopher S., Mariani, Thomas J., Thakar, Juilee, Dewhurst, Stephen, Mathews, David H., Huang, Liang, Sun, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516852/
https://www.ncbi.nlm.nih.gov/pubmed/36172120
http://dx.doi.org/10.1101/2022.09.22.509123
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