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Bioinformatics-based SARS-CoV-2 epitopes design and the impact of spike protein mutants on epitope humoral immunities

BACKGROUND: Epitope selection is the key to peptide vaccines development. Bioinformatics tools can efficiently improve the screening of antigenic epitopes and help to choose the right ones. OBJECTIVE: To predict, synthesize and testify peptide epitopes at spike protein, assess the effect of mutation...

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Detalles Bibliográficos
Autores principales:	Sun, Qi, Huang, Zhuanqing, Yang, Sen, Li, Yuanyuan, Ma, Yue, Yang, Fei, Zhang, Ying, Xu, Fenghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier GmbH. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516880/ https://www.ncbi.nlm.nih.gov/pubmed/36244092 http://dx.doi.org/10.1016/j.imbio.2022.152287

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