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Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma: Case series report

BACKGROUND: Retroperitoneal sarcoma (RPS) is a rare malignancy arising from mesenchymal cells that most commonly presents as an abdominal mass and is associated with poor prognosis. Although several studies have assessed the survival benefits of wide excision, few have reported detailed methods for...

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Autores principales: Song, Heekyoung, Ahn, Jung Hwan, Jung, Yuyeon, Woo, Jae Yeon, Cha, Jimin, Chung, Yang-Guk, Lee, Keun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516929/
https://www.ncbi.nlm.nih.gov/pubmed/36186181
http://dx.doi.org/10.12998/wjcc.v10.i27.9693
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author Song, Heekyoung
Ahn, Jung Hwan
Jung, Yuyeon
Woo, Jae Yeon
Cha, Jimin
Chung, Yang-Guk
Lee, Keun Ho
author_facet Song, Heekyoung
Ahn, Jung Hwan
Jung, Yuyeon
Woo, Jae Yeon
Cha, Jimin
Chung, Yang-Guk
Lee, Keun Ho
author_sort Song, Heekyoung
collection PubMed
description BACKGROUND: Retroperitoneal sarcoma (RPS) is a rare malignancy arising from mesenchymal cells that most commonly presents as an abdominal mass and is associated with poor prognosis. Although several studies have assessed the survival benefits of wide excision, few have reported detailed methods for achieving wide excision in patients with RPS. AIM: To describe our experience with multidisciplinary surgical resection of RPS using intra- and extra-pelvic approaches. METHODS: Multidisciplinary surgery is an anatomical approach that combines intra- and extra-peritoneal access within the same surgery to achieve complete RPS removal. This retrospective review of the records of patients who underwent multidisciplinary surgery for RPS analyzed surgical and survival outcomes. RESULTS: Eight patients underwent 10 intra- and extra-pelvic surgical resections, and their median mass size was 12.75 cm (range, 6-45.5 cm). Using an intrapelvic approach, laparoscopy-assisted surgery was performed in four cases and laparotomy surgery in six. Using an extrapelvic approach, ilioinguinal and posterior approaches were used in four cases each, and the prone position and midline skin incision were shared in one. All patients’ RPS masses were removed completely, and four achieved R0 resection through intra- and extra-pelvic surgery. The median estimated blood loss was 2000 mL (range, 300-20000 mL) and the median hospitalization was 12.6 d (range, 9-69 d). Reoperation was needed in two patients (one for wound necrosis and the other for bowel perforation and wound necrosis). The median overall survival rate and median progression-free survival were 64.6 and 13.7 mo, respectively. CONCLUSION: RPS is therapeutically challenging because of its location and high risk of recurrence. Therefore, intra- and extra-pelvic surgical approaches can improve the macroscopic security of the surgical margin.
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spelling pubmed-95169292022-09-29 Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma: Case series report Song, Heekyoung Ahn, Jung Hwan Jung, Yuyeon Woo, Jae Yeon Cha, Jimin Chung, Yang-Guk Lee, Keun Ho World J Clin Cases Observational Study BACKGROUND: Retroperitoneal sarcoma (RPS) is a rare malignancy arising from mesenchymal cells that most commonly presents as an abdominal mass and is associated with poor prognosis. Although several studies have assessed the survival benefits of wide excision, few have reported detailed methods for achieving wide excision in patients with RPS. AIM: To describe our experience with multidisciplinary surgical resection of RPS using intra- and extra-pelvic approaches. METHODS: Multidisciplinary surgery is an anatomical approach that combines intra- and extra-peritoneal access within the same surgery to achieve complete RPS removal. This retrospective review of the records of patients who underwent multidisciplinary surgery for RPS analyzed surgical and survival outcomes. RESULTS: Eight patients underwent 10 intra- and extra-pelvic surgical resections, and their median mass size was 12.75 cm (range, 6-45.5 cm). Using an intrapelvic approach, laparoscopy-assisted surgery was performed in four cases and laparotomy surgery in six. Using an extrapelvic approach, ilioinguinal and posterior approaches were used in four cases each, and the prone position and midline skin incision were shared in one. All patients’ RPS masses were removed completely, and four achieved R0 resection through intra- and extra-pelvic surgery. The median estimated blood loss was 2000 mL (range, 300-20000 mL) and the median hospitalization was 12.6 d (range, 9-69 d). Reoperation was needed in two patients (one for wound necrosis and the other for bowel perforation and wound necrosis). The median overall survival rate and median progression-free survival were 64.6 and 13.7 mo, respectively. CONCLUSION: RPS is therapeutically challenging because of its location and high risk of recurrence. Therefore, intra- and extra-pelvic surgical approaches can improve the macroscopic security of the surgical margin. Baishideng Publishing Group Inc 2022-09-26 2022-09-26 /pmc/articles/PMC9516929/ /pubmed/36186181 http://dx.doi.org/10.12998/wjcc.v10.i27.9693 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Observational Study
Song, Heekyoung
Ahn, Jung Hwan
Jung, Yuyeon
Woo, Jae Yeon
Cha, Jimin
Chung, Yang-Guk
Lee, Keun Ho
Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma: Case series report
title Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma: Case series report
title_full Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma: Case series report
title_fullStr Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma: Case series report
title_full_unstemmed Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma: Case series report
title_short Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma: Case series report
title_sort intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma: case series report
topic Observational Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516929/
https://www.ncbi.nlm.nih.gov/pubmed/36186181
http://dx.doi.org/10.12998/wjcc.v10.i27.9693
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