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Psychometric Properties of the Functional Impairment Checklist (FIC) as a Disease-Specific Patient-Reported Outcome Measure (PROM) in Previously Hospitalized COVID-19 Survivors with Long-COVID

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is associated with a plethora of long-lasting symptoms (long-COVID). The presence of long-COVID symptoms causes decreased functionality. This study described the psychometric properties of the Functional Impairment Checklist (FIC...

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Autores principales: Fernández-de-las-Peñas, César, Palacios-Ceña, Maria, Rodríguez-Jiménez, Jorge, de-la-Llave-Rincón, Ana I., Fuensalida-Novo, Stella, Cigarán-Méndez, Margarita, Florencio, Lidiane L., Ambite-Quesada, Silvia, Ortega-Santiago, Ricardo, Pardo-Hernández, Alberto, Hernández-Barrera, Valentín, Palacios-Ceña, Domingo, Gil-de-Miguel, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9517100/
https://www.ncbi.nlm.nih.gov/pubmed/36141732
http://dx.doi.org/10.3390/ijerph191811460
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author Fernández-de-las-Peñas, César
Palacios-Ceña, Maria
Rodríguez-Jiménez, Jorge
de-la-Llave-Rincón, Ana I.
Fuensalida-Novo, Stella
Cigarán-Méndez, Margarita
Florencio, Lidiane L.
Ambite-Quesada, Silvia
Ortega-Santiago, Ricardo
Pardo-Hernández, Alberto
Hernández-Barrera, Valentín
Palacios-Ceña, Domingo
Gil-de-Miguel, Ángel
author_facet Fernández-de-las-Peñas, César
Palacios-Ceña, Maria
Rodríguez-Jiménez, Jorge
de-la-Llave-Rincón, Ana I.
Fuensalida-Novo, Stella
Cigarán-Méndez, Margarita
Florencio, Lidiane L.
Ambite-Quesada, Silvia
Ortega-Santiago, Ricardo
Pardo-Hernández, Alberto
Hernández-Barrera, Valentín
Palacios-Ceña, Domingo
Gil-de-Miguel, Ángel
author_sort Fernández-de-las-Peñas, César
collection PubMed
description The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is associated with a plethora of long-lasting symptoms (long-COVID). The presence of long-COVID symptoms causes decreased functionality. This study described the psychometric properties of the Functional Impairment Checklist (FIC), a disease-specific patient-reported outcome measure (PROM) used for evaluating the functional consequences of SARS in previously hospitalized COVID-19 survivors with long-COVID symptoms. The LONG-COVID-EXP-CM is a multicenter cohort study including patients hospitalized with COVID-19 during the first wave of the pandemic in five hospitals in Madrid. A total of 1969 (age: 61 ± 16 years, 46.4% women) COVID-19 survivors with long-COVID completed the FIC at a long-term follow-up after hospitalization (mean: 8.4 ± 1.5 months). Internal consistency (Cronbach alpha value), reliability (item-internal consistency, item-discriminant validity), construct validity (exploratory factor analysis), floor effect and ceiling effect were calculated. The mean time for fulfilling the FIC was 62 ± 11 s. The Cronbach’s alpha values reflecting the internal consistency reliability were 0.864 for FIC-symptoms and 0.845 for FIC-disability. The correlation coefficient between the FIC-symptoms and FIC-disability scale was good (r: 0.676). The ceiling effect ranged from 2.29% to 9.02%, whereas the floor effect ranged from 38.56% to 80.19%. The exploratory factor analysis showed factor loadings from 0.514 to 0.866, supporting good construct validity. Women exhibited greater limitations in all physical symptoms and disability-related domains of the FIC compared with men (all, p < 0.001). Further, younger patients (those aged <45 years) self-reported lower physical symptoms and disability-related domains than older patients. In conclusion, this study indicates that the FIC has good psychometric properties to be used as a specific-disease PROM to measure function and disability in COVID-19 survivors with long-COVID.
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spelling pubmed-95171002022-09-29 Psychometric Properties of the Functional Impairment Checklist (FIC) as a Disease-Specific Patient-Reported Outcome Measure (PROM) in Previously Hospitalized COVID-19 Survivors with Long-COVID Fernández-de-las-Peñas, César Palacios-Ceña, Maria Rodríguez-Jiménez, Jorge de-la-Llave-Rincón, Ana I. Fuensalida-Novo, Stella Cigarán-Méndez, Margarita Florencio, Lidiane L. Ambite-Quesada, Silvia Ortega-Santiago, Ricardo Pardo-Hernández, Alberto Hernández-Barrera, Valentín Palacios-Ceña, Domingo Gil-de-Miguel, Ángel Int J Environ Res Public Health Article The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is associated with a plethora of long-lasting symptoms (long-COVID). The presence of long-COVID symptoms causes decreased functionality. This study described the psychometric properties of the Functional Impairment Checklist (FIC), a disease-specific patient-reported outcome measure (PROM) used for evaluating the functional consequences of SARS in previously hospitalized COVID-19 survivors with long-COVID symptoms. The LONG-COVID-EXP-CM is a multicenter cohort study including patients hospitalized with COVID-19 during the first wave of the pandemic in five hospitals in Madrid. A total of 1969 (age: 61 ± 16 years, 46.4% women) COVID-19 survivors with long-COVID completed the FIC at a long-term follow-up after hospitalization (mean: 8.4 ± 1.5 months). Internal consistency (Cronbach alpha value), reliability (item-internal consistency, item-discriminant validity), construct validity (exploratory factor analysis), floor effect and ceiling effect were calculated. The mean time for fulfilling the FIC was 62 ± 11 s. The Cronbach’s alpha values reflecting the internal consistency reliability were 0.864 for FIC-symptoms and 0.845 for FIC-disability. The correlation coefficient between the FIC-symptoms and FIC-disability scale was good (r: 0.676). The ceiling effect ranged from 2.29% to 9.02%, whereas the floor effect ranged from 38.56% to 80.19%. The exploratory factor analysis showed factor loadings from 0.514 to 0.866, supporting good construct validity. Women exhibited greater limitations in all physical symptoms and disability-related domains of the FIC compared with men (all, p < 0.001). Further, younger patients (those aged <45 years) self-reported lower physical symptoms and disability-related domains than older patients. In conclusion, this study indicates that the FIC has good psychometric properties to be used as a specific-disease PROM to measure function and disability in COVID-19 survivors with long-COVID. MDPI 2022-09-12 /pmc/articles/PMC9517100/ /pubmed/36141732 http://dx.doi.org/10.3390/ijerph191811460 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fernández-de-las-Peñas, César
Palacios-Ceña, Maria
Rodríguez-Jiménez, Jorge
de-la-Llave-Rincón, Ana I.
Fuensalida-Novo, Stella
Cigarán-Méndez, Margarita
Florencio, Lidiane L.
Ambite-Quesada, Silvia
Ortega-Santiago, Ricardo
Pardo-Hernández, Alberto
Hernández-Barrera, Valentín
Palacios-Ceña, Domingo
Gil-de-Miguel, Ángel
Psychometric Properties of the Functional Impairment Checklist (FIC) as a Disease-Specific Patient-Reported Outcome Measure (PROM) in Previously Hospitalized COVID-19 Survivors with Long-COVID
title Psychometric Properties of the Functional Impairment Checklist (FIC) as a Disease-Specific Patient-Reported Outcome Measure (PROM) in Previously Hospitalized COVID-19 Survivors with Long-COVID
title_full Psychometric Properties of the Functional Impairment Checklist (FIC) as a Disease-Specific Patient-Reported Outcome Measure (PROM) in Previously Hospitalized COVID-19 Survivors with Long-COVID
title_fullStr Psychometric Properties of the Functional Impairment Checklist (FIC) as a Disease-Specific Patient-Reported Outcome Measure (PROM) in Previously Hospitalized COVID-19 Survivors with Long-COVID
title_full_unstemmed Psychometric Properties of the Functional Impairment Checklist (FIC) as a Disease-Specific Patient-Reported Outcome Measure (PROM) in Previously Hospitalized COVID-19 Survivors with Long-COVID
title_short Psychometric Properties of the Functional Impairment Checklist (FIC) as a Disease-Specific Patient-Reported Outcome Measure (PROM) in Previously Hospitalized COVID-19 Survivors with Long-COVID
title_sort psychometric properties of the functional impairment checklist (fic) as a disease-specific patient-reported outcome measure (prom) in previously hospitalized covid-19 survivors with long-covid
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9517100/
https://www.ncbi.nlm.nih.gov/pubmed/36141732
http://dx.doi.org/10.3390/ijerph191811460
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