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Psychological Stress Triggers a Hyperammonemia Episode in Patient with Ornithine Transcarbamylase Deficiency

An 18-year-old male motorcycle racer, who was a participant in the FIM Road Racing World Championship and had a history of Ornithine Transcarbamylase deficiency, developed nausea and dizziness while driving his motorcycle and became unconscious right after he stopped at the box. He was rapidly atten...

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Autores principales: Fernández-Elías, Valentín Emilio, Tornero-Aguilera, José Francisco, Parraca, Jose Alberto, Clemente-Suárez, Vicente Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9517620/
https://www.ncbi.nlm.nih.gov/pubmed/36141788
http://dx.doi.org/10.3390/ijerph191811516
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author Fernández-Elías, Valentín Emilio
Tornero-Aguilera, José Francisco
Parraca, Jose Alberto
Clemente-Suárez, Vicente Javier
author_facet Fernández-Elías, Valentín Emilio
Tornero-Aguilera, José Francisco
Parraca, Jose Alberto
Clemente-Suárez, Vicente Javier
author_sort Fernández-Elías, Valentín Emilio
collection PubMed
description An 18-year-old male motorcycle racer, who was a participant in the FIM Road Racing World Championship and had a history of Ornithine Transcarbamylase deficiency, developed nausea and dizziness while driving his motorcycle and became unconscious right after he stopped at the box. He was rapidly attended to by the medical personnel of the circuit, and once he recovered consciousness, he was taken to the local hospital where the blood analysis showed hyperammonemia (307 μg/dL) and excess alkalosis. The patient was properly following the prescribed treatment, and there were no environmental stressors. Hence, psychological stress and its somatization due to the risky task that the patient was performing could have triggered the episode. Stress must be considered as a potential cause, triggering strenuous metabolic stress that leads to hyperammonemia.
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spelling pubmed-95176202022-09-29 Psychological Stress Triggers a Hyperammonemia Episode in Patient with Ornithine Transcarbamylase Deficiency Fernández-Elías, Valentín Emilio Tornero-Aguilera, José Francisco Parraca, Jose Alberto Clemente-Suárez, Vicente Javier Int J Environ Res Public Health Case Report An 18-year-old male motorcycle racer, who was a participant in the FIM Road Racing World Championship and had a history of Ornithine Transcarbamylase deficiency, developed nausea and dizziness while driving his motorcycle and became unconscious right after he stopped at the box. He was rapidly attended to by the medical personnel of the circuit, and once he recovered consciousness, he was taken to the local hospital where the blood analysis showed hyperammonemia (307 μg/dL) and excess alkalosis. The patient was properly following the prescribed treatment, and there were no environmental stressors. Hence, psychological stress and its somatization due to the risky task that the patient was performing could have triggered the episode. Stress must be considered as a potential cause, triggering strenuous metabolic stress that leads to hyperammonemia. MDPI 2022-09-13 /pmc/articles/PMC9517620/ /pubmed/36141788 http://dx.doi.org/10.3390/ijerph191811516 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Fernández-Elías, Valentín Emilio
Tornero-Aguilera, José Francisco
Parraca, Jose Alberto
Clemente-Suárez, Vicente Javier
Psychological Stress Triggers a Hyperammonemia Episode in Patient with Ornithine Transcarbamylase Deficiency
title Psychological Stress Triggers a Hyperammonemia Episode in Patient with Ornithine Transcarbamylase Deficiency
title_full Psychological Stress Triggers a Hyperammonemia Episode in Patient with Ornithine Transcarbamylase Deficiency
title_fullStr Psychological Stress Triggers a Hyperammonemia Episode in Patient with Ornithine Transcarbamylase Deficiency
title_full_unstemmed Psychological Stress Triggers a Hyperammonemia Episode in Patient with Ornithine Transcarbamylase Deficiency
title_short Psychological Stress Triggers a Hyperammonemia Episode in Patient with Ornithine Transcarbamylase Deficiency
title_sort psychological stress triggers a hyperammonemia episode in patient with ornithine transcarbamylase deficiency
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9517620/
https://www.ncbi.nlm.nih.gov/pubmed/36141788
http://dx.doi.org/10.3390/ijerph191811516
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