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Local Hyperbaric Oxygen Therapy in the Treatment of Diabetic Foot Ulcers

Background: Diabetes mellitus is one of the most common metabolic diseases. The most serious complication of diabetes is diabetic foot ulcer, which affects several million people around the world each year. In recent years, increasingly modern methods of physical medicine including hyperbaric oxygen...

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Autores principales: Pasek, Jarosław, Szajkowski, Sebastian, Oleś, Piotr, Cieślar, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518160/
https://www.ncbi.nlm.nih.gov/pubmed/36078262
http://dx.doi.org/10.3390/ijerph191710548
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author Pasek, Jarosław
Szajkowski, Sebastian
Oleś, Piotr
Cieślar, Grzegorz
author_facet Pasek, Jarosław
Szajkowski, Sebastian
Oleś, Piotr
Cieślar, Grzegorz
author_sort Pasek, Jarosław
collection PubMed
description Background: Diabetes mellitus is one of the most common metabolic diseases. The most serious complication of diabetes is diabetic foot ulcer, which affects several million people around the world each year. In recent years, increasingly modern methods of physical medicine including hyperbaric oxygen therapy have been used often in the complex therapy of this complication. Methods: This study included 45 patients, 24 male (53.3%) and 21 female (46.6%), whose age was between 49 and 83 years (mean age: 66.7 ± 8.8 years) with diabetes lasting for 1.5–18 years, who underwent local hyperbaric oxygen therapy at the pressure of 2.5 ATA (30 exposures for 30 min each) due to diabetic foot ulcers. The progress in wound healing before and after the end of therapy was evaluated by computerized planimetry, and the pain intensity was assessed with the use of a VAS. Results: The analysis of results showed a statistically significant reduction in the wound surface area after the treatment, from 8.54 ± 3.34 cm to 4.23 ± 3.23 cm² (p = 0.000001). In 5 patients (11.1%), the wounds were healed completely. In 25 patients (55.5%), the topical state of the wound surface was significantly decreased by 50% on average. There was also a significant reduction in the perceived pain on the VAS in all examined patients from 4.64 ± 1.68 points before treatment to 1.51 ± 0.92 points after treatment (p = 0.000001). Conclusions: The application of local HBO therapy in the treatment of diabetic foot ulcers accelerates the ulcer healing process, as judged in objective planimetric assessment, and reduces the intensity of perceived pain ailments.
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spelling pubmed-95181602022-09-29 Local Hyperbaric Oxygen Therapy in the Treatment of Diabetic Foot Ulcers Pasek, Jarosław Szajkowski, Sebastian Oleś, Piotr Cieślar, Grzegorz Int J Environ Res Public Health Article Background: Diabetes mellitus is one of the most common metabolic diseases. The most serious complication of diabetes is diabetic foot ulcer, which affects several million people around the world each year. In recent years, increasingly modern methods of physical medicine including hyperbaric oxygen therapy have been used often in the complex therapy of this complication. Methods: This study included 45 patients, 24 male (53.3%) and 21 female (46.6%), whose age was between 49 and 83 years (mean age: 66.7 ± 8.8 years) with diabetes lasting for 1.5–18 years, who underwent local hyperbaric oxygen therapy at the pressure of 2.5 ATA (30 exposures for 30 min each) due to diabetic foot ulcers. The progress in wound healing before and after the end of therapy was evaluated by computerized planimetry, and the pain intensity was assessed with the use of a VAS. Results: The analysis of results showed a statistically significant reduction in the wound surface area after the treatment, from 8.54 ± 3.34 cm to 4.23 ± 3.23 cm² (p = 0.000001). In 5 patients (11.1%), the wounds were healed completely. In 25 patients (55.5%), the topical state of the wound surface was significantly decreased by 50% on average. There was also a significant reduction in the perceived pain on the VAS in all examined patients from 4.64 ± 1.68 points before treatment to 1.51 ± 0.92 points after treatment (p = 0.000001). Conclusions: The application of local HBO therapy in the treatment of diabetic foot ulcers accelerates the ulcer healing process, as judged in objective planimetric assessment, and reduces the intensity of perceived pain ailments. MDPI 2022-08-24 /pmc/articles/PMC9518160/ /pubmed/36078262 http://dx.doi.org/10.3390/ijerph191710548 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pasek, Jarosław
Szajkowski, Sebastian
Oleś, Piotr
Cieślar, Grzegorz
Local Hyperbaric Oxygen Therapy in the Treatment of Diabetic Foot Ulcers
title Local Hyperbaric Oxygen Therapy in the Treatment of Diabetic Foot Ulcers
title_full Local Hyperbaric Oxygen Therapy in the Treatment of Diabetic Foot Ulcers
title_fullStr Local Hyperbaric Oxygen Therapy in the Treatment of Diabetic Foot Ulcers
title_full_unstemmed Local Hyperbaric Oxygen Therapy in the Treatment of Diabetic Foot Ulcers
title_short Local Hyperbaric Oxygen Therapy in the Treatment of Diabetic Foot Ulcers
title_sort local hyperbaric oxygen therapy in the treatment of diabetic foot ulcers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518160/
https://www.ncbi.nlm.nih.gov/pubmed/36078262
http://dx.doi.org/10.3390/ijerph191710548
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