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Activation of AMPK-PGC-1α pathway ameliorates peritoneal dialysis related peritoneal fibrosis in mice by enhancing mitochondrial biogenesis

BACKGROUND: The pathogenesis of peritoneal dialysis (PD)-related peritoneal fibrosis (PF) is not clearly understood, and current treatment options are limited. METHODS: In this study, the effect of PD-related PF on mitochondrial biogenesis was investigated, and the effect of activation of the adenos...

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Detalles Bibliográficos
Autores principales: Wu, Jun, Li, Jushuang, Feng, Baohong, Bi, Zhimin, Zhu, Geli, Zhang, Yanxia, Li, Xiangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518249/
https://www.ncbi.nlm.nih.gov/pubmed/36148521
http://dx.doi.org/10.1080/0886022X.2022.2126789