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Preventable Cancer in Israel

Background: The cancer burden in Israel is substantial. Recently calculated population attributable fractions (PAFs) for modifiable cancer risk factors in the US and the UK have indicated much room for prevention. Our aim was to estimate PAFs for selected modifiable cancer risk factors in Israel. Me...

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Autores principales: Magid, Avi, Robinson, Eliezer, Keinan-Boker, Lital
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518384/
https://www.ncbi.nlm.nih.gov/pubmed/36078236
http://dx.doi.org/10.3390/ijerph191710521
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author Magid, Avi
Robinson, Eliezer
Keinan-Boker, Lital
author_facet Magid, Avi
Robinson, Eliezer
Keinan-Boker, Lital
author_sort Magid, Avi
collection PubMed
description Background: The cancer burden in Israel is substantial. Recently calculated population attributable fractions (PAFs) for modifiable cancer risk factors in the US and the UK have indicated much room for prevention. Our aim was to estimate PAFs for selected modifiable cancer risk factors in Israel. Methods: Exposure data on selected modifiable risk factors were based on national health surveys conducted in 2013–2015. Data on invasive cancer incidence in 2015 were retrieved from the Israel National Cancer Registry (INCR). Relative risks (RRs) for specific cancer sites were retrieved from the scientific literature. PAFs were calculated for selected modifiable risk factors using an approximate formula. Results: In 2015, 21% of all invasive cancer cases in Israel were attributed to smoking, 9% to excess body weight, and 1.5% to alcohol intake. Moreover, 32% of all invasive cancer cases were attributed to all modifiable risk factors (combined) included in our study. Conclusions: Quantifying the contribution of modifiable risk factors to the incidence of certain cancer types in Israel offers an opportunity for primary prevention and enables informed decision-making with respect to the prioritization of interventions.
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spelling pubmed-95183842022-09-29 Preventable Cancer in Israel Magid, Avi Robinson, Eliezer Keinan-Boker, Lital Int J Environ Res Public Health Article Background: The cancer burden in Israel is substantial. Recently calculated population attributable fractions (PAFs) for modifiable cancer risk factors in the US and the UK have indicated much room for prevention. Our aim was to estimate PAFs for selected modifiable cancer risk factors in Israel. Methods: Exposure data on selected modifiable risk factors were based on national health surveys conducted in 2013–2015. Data on invasive cancer incidence in 2015 were retrieved from the Israel National Cancer Registry (INCR). Relative risks (RRs) for specific cancer sites were retrieved from the scientific literature. PAFs were calculated for selected modifiable risk factors using an approximate formula. Results: In 2015, 21% of all invasive cancer cases in Israel were attributed to smoking, 9% to excess body weight, and 1.5% to alcohol intake. Moreover, 32% of all invasive cancer cases were attributed to all modifiable risk factors (combined) included in our study. Conclusions: Quantifying the contribution of modifiable risk factors to the incidence of certain cancer types in Israel offers an opportunity for primary prevention and enables informed decision-making with respect to the prioritization of interventions. MDPI 2022-08-24 /pmc/articles/PMC9518384/ /pubmed/36078236 http://dx.doi.org/10.3390/ijerph191710521 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Magid, Avi
Robinson, Eliezer
Keinan-Boker, Lital
Preventable Cancer in Israel
title Preventable Cancer in Israel
title_full Preventable Cancer in Israel
title_fullStr Preventable Cancer in Israel
title_full_unstemmed Preventable Cancer in Israel
title_short Preventable Cancer in Israel
title_sort preventable cancer in israel
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518384/
https://www.ncbi.nlm.nih.gov/pubmed/36078236
http://dx.doi.org/10.3390/ijerph191710521
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