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Comparing PTSD symptom networks in type I vs. type II trauma survivors

Background: Network analysis has gained increasing attention as a new framework to study complex associations between symptoms of post-traumatic stress disorder (PTSD). A number of studies have been published to investigate symptom networks on different sets of symptoms in different populations, and...

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Autores principales: Stefanovic, Mina, Ehring, Thomas, Wittekind, Charlotte E., Kleim, Birgit, Rohde, Judith, Krüger-Gottschalk, Antje, Knaevelsrud, Christine, Rau, Heinrich, Schäfer, Ingo, Schellong, Julia, Dyer, Anne, Takano, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518442/
https://www.ncbi.nlm.nih.gov/pubmed/36186163
http://dx.doi.org/10.1080/20008066.2022.2114260
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author Stefanovic, Mina
Ehring, Thomas
Wittekind, Charlotte E.
Kleim, Birgit
Rohde, Judith
Krüger-Gottschalk, Antje
Knaevelsrud, Christine
Rau, Heinrich
Schäfer, Ingo
Schellong, Julia
Dyer, Anne
Takano, Keisuke
author_facet Stefanovic, Mina
Ehring, Thomas
Wittekind, Charlotte E.
Kleim, Birgit
Rohde, Judith
Krüger-Gottschalk, Antje
Knaevelsrud, Christine
Rau, Heinrich
Schäfer, Ingo
Schellong, Julia
Dyer, Anne
Takano, Keisuke
author_sort Stefanovic, Mina
collection PubMed
description Background: Network analysis has gained increasing attention as a new framework to study complex associations between symptoms of post-traumatic stress disorder (PTSD). A number of studies have been published to investigate symptom networks on different sets of symptoms in different populations, and the findings have been inconsistent. Objective: We aimed to extend previous research by testing whether differences in PTSD symptom networks can be found in survivors of type I (single event; sudden and unexpected, high levels of acute threat) vs. type II (repeated and/or protracted; anticipated) trauma (with regard to their index trauma). Method: Participants were trauma-exposed individuals with elevated levels of PTSD symptomatology, most of whom (94%) were undergoing assessment in preparation for PTSD treatment in several treatment centres in Germany and Switzerland (n = 286 with type I and n = 187 with type II trauma). We estimated Bayesian Gaussian graphical models for each trauma group and explored group differences in the symptom network. Results: First, for both trauma types, our analyses identified the edges that were repeatedly reported in previous network studies. Second, there was decisive evidence that the two networks were generated from different multivariate normal distributions, i.e. the networks differed on a global level. Third, explorative edge-wise comparisons showed moderate or strong evidence for specific 12 edges. Edges which emerged as especially important in distinguishing the networks were between intrusions and flashbacks, highlighting the stronger positive association in the group of type II trauma survivors compared to type I survivors. Flashbacks showed a similar pattern of results in the associations with detachment and sleep problems (type II > type I). Conclusion: Our findings suggest that trauma type contributes to the heterogeneity in the symptom network. Future research on PTSD symptom networks should include this variable in the analyses to reduce heterogeneity.
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spelling pubmed-95184422022-09-29 Comparing PTSD symptom networks in type I vs. type II trauma survivors Stefanovic, Mina Ehring, Thomas Wittekind, Charlotte E. Kleim, Birgit Rohde, Judith Krüger-Gottschalk, Antje Knaevelsrud, Christine Rau, Heinrich Schäfer, Ingo Schellong, Julia Dyer, Anne Takano, Keisuke Eur J Psychotraumatol Clinical Research Article Background: Network analysis has gained increasing attention as a new framework to study complex associations between symptoms of post-traumatic stress disorder (PTSD). A number of studies have been published to investigate symptom networks on different sets of symptoms in different populations, and the findings have been inconsistent. Objective: We aimed to extend previous research by testing whether differences in PTSD symptom networks can be found in survivors of type I (single event; sudden and unexpected, high levels of acute threat) vs. type II (repeated and/or protracted; anticipated) trauma (with regard to their index trauma). Method: Participants were trauma-exposed individuals with elevated levels of PTSD symptomatology, most of whom (94%) were undergoing assessment in preparation for PTSD treatment in several treatment centres in Germany and Switzerland (n = 286 with type I and n = 187 with type II trauma). We estimated Bayesian Gaussian graphical models for each trauma group and explored group differences in the symptom network. Results: First, for both trauma types, our analyses identified the edges that were repeatedly reported in previous network studies. Second, there was decisive evidence that the two networks were generated from different multivariate normal distributions, i.e. the networks differed on a global level. Third, explorative edge-wise comparisons showed moderate or strong evidence for specific 12 edges. Edges which emerged as especially important in distinguishing the networks were between intrusions and flashbacks, highlighting the stronger positive association in the group of type II trauma survivors compared to type I survivors. Flashbacks showed a similar pattern of results in the associations with detachment and sleep problems (type II > type I). Conclusion: Our findings suggest that trauma type contributes to the heterogeneity in the symptom network. Future research on PTSD symptom networks should include this variable in the analyses to reduce heterogeneity. Taylor & Francis 2022-09-21 /pmc/articles/PMC9518442/ /pubmed/36186163 http://dx.doi.org/10.1080/20008066.2022.2114260 Text en © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research Article
Stefanovic, Mina
Ehring, Thomas
Wittekind, Charlotte E.
Kleim, Birgit
Rohde, Judith
Krüger-Gottschalk, Antje
Knaevelsrud, Christine
Rau, Heinrich
Schäfer, Ingo
Schellong, Julia
Dyer, Anne
Takano, Keisuke
Comparing PTSD symptom networks in type I vs. type II trauma survivors
title Comparing PTSD symptom networks in type I vs. type II trauma survivors
title_full Comparing PTSD symptom networks in type I vs. type II trauma survivors
title_fullStr Comparing PTSD symptom networks in type I vs. type II trauma survivors
title_full_unstemmed Comparing PTSD symptom networks in type I vs. type II trauma survivors
title_short Comparing PTSD symptom networks in type I vs. type II trauma survivors
title_sort comparing ptsd symptom networks in type i vs. type ii trauma survivors
topic Clinical Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518442/
https://www.ncbi.nlm.nih.gov/pubmed/36186163
http://dx.doi.org/10.1080/20008066.2022.2114260
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