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The BCL2/BAX/ROS pathway is involved in the inhibitory effect of astragaloside IV on pyroptosis in human umbilical vein endothelial cells

CONTEXT: Astragaloside IV (AS-IV) is extracted from Astragalus membranaceus (Fisch.) Bunge (Fabaceae). However, its effects on endothelial cell injury remain unclear. OBJECTIVE: To investigate the mechanisms underlying the effects of AS-IV on lipopolysaccharide (LPS)-induced endothelial injury in vi...

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Detalles Bibliográficos
Autores principales: Su, Yi, Yin, Xin, Huang, Xin, Guo, Qianqian, Ma, Mingyuan, Guo, Liheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518636/
https://www.ncbi.nlm.nih.gov/pubmed/36121248
http://dx.doi.org/10.1080/13880209.2022.2101668

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