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Development of a nomogram prediction model for depression in patients with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease with depression as one of its most common symptoms. The aim of this study is to establish a nomogram prediction model to assess the occurrence of depression in patients with SLE. Based on the Hospital Anxiety and Depression Sca...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518674/ https://www.ncbi.nlm.nih.gov/pubmed/36186364 http://dx.doi.org/10.3389/fpsyg.2022.951431 |
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author | Chen, Haoyang Cui, Hengmei Geng, Yaqin Jin, Tiantian Shi, Songsong Li, Yunyun Chen, Xin Shen, Biyu |
author_facet | Chen, Haoyang Cui, Hengmei Geng, Yaqin Jin, Tiantian Shi, Songsong Li, Yunyun Chen, Xin Shen, Biyu |
author_sort | Chen, Haoyang |
collection | PubMed |
description | Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease with depression as one of its most common symptoms. The aim of this study is to establish a nomogram prediction model to assess the occurrence of depression in patients with SLE. Based on the Hospital Anxiety and Depression Scale cutoff of 8, 341 patients with SLE, recruited between June 2017 and December 2019, were divided into depressive and non-depressive groups. Data on socio-demographic characteristics, medical history, sociopsychological factors, and other risk factors were collected. Between-group differences in clinical characteristics were assessed with depression as the dependent variable and the variables selected by logistic multiple regression as predictors. The model was established using R language. Marital status, education, social support, coping, and anxiety predicted depression (p < 0.05). The nomogram prediction model showed that the risk rate was from 0.01 to 0.80, and the receiver operating characteristic curve analysis showed that the area under the curve was 0.891 (p < 0.001). The calibration curve can intuitively show that the probability of depression predicted by the nomogram model is consistent with the actual comparison. The designed nomogram provides a highly predictive assessment of depression in patients with SLE, facilitating more comprehensive depression evaluation in usual clinical care. |
format | Online Article Text |
id | pubmed-9518674 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95186742022-09-29 Development of a nomogram prediction model for depression in patients with systemic lupus erythematosus Chen, Haoyang Cui, Hengmei Geng, Yaqin Jin, Tiantian Shi, Songsong Li, Yunyun Chen, Xin Shen, Biyu Front Psychol Psychology Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease with depression as one of its most common symptoms. The aim of this study is to establish a nomogram prediction model to assess the occurrence of depression in patients with SLE. Based on the Hospital Anxiety and Depression Scale cutoff of 8, 341 patients with SLE, recruited between June 2017 and December 2019, were divided into depressive and non-depressive groups. Data on socio-demographic characteristics, medical history, sociopsychological factors, and other risk factors were collected. Between-group differences in clinical characteristics were assessed with depression as the dependent variable and the variables selected by logistic multiple regression as predictors. The model was established using R language. Marital status, education, social support, coping, and anxiety predicted depression (p < 0.05). The nomogram prediction model showed that the risk rate was from 0.01 to 0.80, and the receiver operating characteristic curve analysis showed that the area under the curve was 0.891 (p < 0.001). The calibration curve can intuitively show that the probability of depression predicted by the nomogram model is consistent with the actual comparison. The designed nomogram provides a highly predictive assessment of depression in patients with SLE, facilitating more comprehensive depression evaluation in usual clinical care. Frontiers Media S.A. 2022-09-14 /pmc/articles/PMC9518674/ /pubmed/36186364 http://dx.doi.org/10.3389/fpsyg.2022.951431 Text en Copyright © 2022 Chen, Cui, Geng, Jin, Shi, Li, Chen and Shen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Psychology Chen, Haoyang Cui, Hengmei Geng, Yaqin Jin, Tiantian Shi, Songsong Li, Yunyun Chen, Xin Shen, Biyu Development of a nomogram prediction model for depression in patients with systemic lupus erythematosus |
title | Development of a nomogram prediction model for depression in patients with systemic lupus erythematosus |
title_full | Development of a nomogram prediction model for depression in patients with systemic lupus erythematosus |
title_fullStr | Development of a nomogram prediction model for depression in patients with systemic lupus erythematosus |
title_full_unstemmed | Development of a nomogram prediction model for depression in patients with systemic lupus erythematosus |
title_short | Development of a nomogram prediction model for depression in patients with systemic lupus erythematosus |
title_sort | development of a nomogram prediction model for depression in patients with systemic lupus erythematosus |
topic | Psychology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518674/ https://www.ncbi.nlm.nih.gov/pubmed/36186364 http://dx.doi.org/10.3389/fpsyg.2022.951431 |
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