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Transcatheter tricuspid valve interventions: Current status and future perspectives

The development of transcatheter therapies to treat valvular heart diseases has changed the rules of the game, particularly in the case of aortic stenosis and mitral regurgitation. In the last years, the tricuspid valve has also been the focus of these percutaneous techniques for several reasons: (1...

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Autores principales: Alperi, Alberto, Almendárez, Marcel, Álvarez, Rut, Moris, Cesar, Leon, Victor, Silva, Iria, Hernández-Vaquero, Daniel, Pascual, Isaac, Avanzas, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518720/
https://www.ncbi.nlm.nih.gov/pubmed/36187002
http://dx.doi.org/10.3389/fcvm.2022.994502
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author Alperi, Alberto
Almendárez, Marcel
Álvarez, Rut
Moris, Cesar
Leon, Victor
Silva, Iria
Hernández-Vaquero, Daniel
Pascual, Isaac
Avanzas, Pablo
author_facet Alperi, Alberto
Almendárez, Marcel
Álvarez, Rut
Moris, Cesar
Leon, Victor
Silva, Iria
Hernández-Vaquero, Daniel
Pascual, Isaac
Avanzas, Pablo
author_sort Alperi, Alberto
collection PubMed
description The development of transcatheter therapies to treat valvular heart diseases has changed the rules of the game, particularly in the case of aortic stenosis and mitral regurgitation. In the last years, the tricuspid valve has also been the focus of these percutaneous techniques for several reasons: (1) tricuspid regurgitation is a frequent disease associated with poor clinical outcomes in spite of medical treatment, leading to end-stage right ventricular heart failure, (2) surgical tricuspid valve repair or replacement has been the treatment of choice for patients with tricuspid valve disease, but high mortality rates for isolated surgical tricuspid valve intervention have been reported in the literature, and (3) most patients with tricuspid pathology are ultimately denied cardiac surgery because of their comorbidity burden. Thus, in this context the development of less invasive catheter-based therapies would be of high clinical relevance. The present review provides an overview regarding the framework of chronic tricuspid regurgitation transcatheter therapeutic options, summarizes the transcatheter systems under clinical use or clinical evaluation with their technical features, and describes the updated current evidence in this challenging and evolving field.
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spelling pubmed-95187202022-09-29 Transcatheter tricuspid valve interventions: Current status and future perspectives Alperi, Alberto Almendárez, Marcel Álvarez, Rut Moris, Cesar Leon, Victor Silva, Iria Hernández-Vaquero, Daniel Pascual, Isaac Avanzas, Pablo Front Cardiovasc Med Cardiovascular Medicine The development of transcatheter therapies to treat valvular heart diseases has changed the rules of the game, particularly in the case of aortic stenosis and mitral regurgitation. In the last years, the tricuspid valve has also been the focus of these percutaneous techniques for several reasons: (1) tricuspid regurgitation is a frequent disease associated with poor clinical outcomes in spite of medical treatment, leading to end-stage right ventricular heart failure, (2) surgical tricuspid valve repair or replacement has been the treatment of choice for patients with tricuspid valve disease, but high mortality rates for isolated surgical tricuspid valve intervention have been reported in the literature, and (3) most patients with tricuspid pathology are ultimately denied cardiac surgery because of their comorbidity burden. Thus, in this context the development of less invasive catheter-based therapies would be of high clinical relevance. The present review provides an overview regarding the framework of chronic tricuspid regurgitation transcatheter therapeutic options, summarizes the transcatheter systems under clinical use or clinical evaluation with their technical features, and describes the updated current evidence in this challenging and evolving field. Frontiers Media S.A. 2022-09-14 /pmc/articles/PMC9518720/ /pubmed/36187002 http://dx.doi.org/10.3389/fcvm.2022.994502 Text en Copyright © 2022 Alperi, Almendárez, Álvarez, Moris, Leon, Silva, Hernández-Vaquero, Pascual and Avanzas. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Alperi, Alberto
Almendárez, Marcel
Álvarez, Rut
Moris, Cesar
Leon, Victor
Silva, Iria
Hernández-Vaquero, Daniel
Pascual, Isaac
Avanzas, Pablo
Transcatheter tricuspid valve interventions: Current status and future perspectives
title Transcatheter tricuspid valve interventions: Current status and future perspectives
title_full Transcatheter tricuspid valve interventions: Current status and future perspectives
title_fullStr Transcatheter tricuspid valve interventions: Current status and future perspectives
title_full_unstemmed Transcatheter tricuspid valve interventions: Current status and future perspectives
title_short Transcatheter tricuspid valve interventions: Current status and future perspectives
title_sort transcatheter tricuspid valve interventions: current status and future perspectives
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518720/
https://www.ncbi.nlm.nih.gov/pubmed/36187002
http://dx.doi.org/10.3389/fcvm.2022.994502
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