Tyk2 is a tumor suppressor in colorectal cancer

Janus kinase Tyk2 is implicated in cancer immune surveillance, but its role in solid tumors is not well defined. We used Tyk2 knockout mice (Tyk2(Δ/Δ)) and mice with conditional deletion of Tyk2 in hematopoietic (Tyk2(ΔHem)) or intestinal epithelial cells (Tyk2(ΔIEC)) to assess their cell type-speci...

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Detalles Bibliográficos
Autores principales: Moritsch, Stefan, Mödl, Bernadette, Scharf, Irene, Janker, Lukas, Zwolanek, Daniela, Timelthaler, Gerald, Casanova, Emilio, Sibilia, Maria, Mohr, Thomas, Kenner, Lukas, Herndler-Brandstetter, Dietmar, Gerner, Christopher, Müller, Mathias, Strobl, Birgit, Eferl, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519006/
https://www.ncbi.nlm.nih.gov/pubmed/36185806
http://dx.doi.org/10.1080/2162402X.2022.2127271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519006/
https://www.ncbi.nlm.nih.gov/pubmed/36185806
http://dx.doi.org/10.1080/2162402X.2022.2127271

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