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Tyk2 is a tumor suppressor in colorectal cancer
Janus kinase Tyk2 is implicated in cancer immune surveillance, but its role in solid tumors is not well defined. We used Tyk2 knockout mice (Tyk2(Δ/Δ)) and mice with conditional deletion of Tyk2 in hematopoietic (Tyk2(ΔHem)) or intestinal epithelial cells (Tyk2(ΔIEC)) to assess their cell type-speci...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519006/ https://www.ncbi.nlm.nih.gov/pubmed/36185806 http://dx.doi.org/10.1080/2162402X.2022.2127271 |