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A novel membrane-bound interleukin-2 promotes NK-92 cell persistence and anti-tumor activity
A major challenge in natural killer (NK) cell immunotherapy is the limited persistence of NK cells in vivo. However, the proliferation of NK cells is dependent on cytokines such as interleukin-2 (IL-2). Although IL-2 is a critical cytokine for NK cell activation and survival, IL-2 administration in...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519007/ https://www.ncbi.nlm.nih.gov/pubmed/36185809 http://dx.doi.org/10.1080/2162402X.2022.2127282 |