A novel membrane-bound interleukin-2 promotes NK-92 cell persistence and anti-tumor activity

A major challenge in natural killer (NK) cell immunotherapy is the limited persistence of NK cells in vivo. However, the proliferation of NK cells is dependent on cytokines such as interleukin-2 (IL-2). Although IL-2 is a critical cytokine for NK cell activation and survival, IL-2 administration in...

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Detalles Bibliográficos
Autores principales: Xiong, Qi, Zhang, Hantao, Ji, Xuanle, Zhang, Yong, Shi, Gang, Dai, Lei, Cheng, Fuyi, Wang, Huiling, Luo, Jieyan, Xu, Jia, Ji, Yanhong, Su, Xiaolan, Yang, Weixiao, Zhang, Lin, Deng, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519007/
https://www.ncbi.nlm.nih.gov/pubmed/36185809
http://dx.doi.org/10.1080/2162402X.2022.2127282

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