Cargando…

Small extracellular vesicles: multi-faceted tools for leukemia immune evasion in vivo

Recently, small extracellular vesicles (sEVs) secreted in vivo from chronic lymphocytic leukemia (CLL) preclinical murine models were characterized. Leukemia microenvironment sEV (LME-sEVs) selectively target CD8(+) T-cells, inducing exhaustion and hampering anti-tumor immune response. Additionally,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gargiulo, Ernesto, Viry, Elodie, Moussay, Etienne, Paggetti, Jerome
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Author’s View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519017/ https://www.ncbi.nlm.nih.gov/pubmed/36185808 http://dx.doi.org/10.1080/2162402X.2022.2127507

Ejemplares similares

Interleukin-27 tackles immunosuppression in chronic lymphocytic leukemia
por: Fernandez Botana, Iria, et al.
Publicado: (2023)

High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia
por: Wierz, Marina, et al.
Publicado: (2018)

Hematological Malignancy-Derived Small Extracellular Vesicles and Tumor Microenvironment: The Art of Turning Foes into Friends
por: Gargiulo, Ernesto, et al.
Publicado: (2019)

Driving Natural Killer cells toward the melanoma tumor battlefield: Autophagy as a valuable therapeutic target
por: Noman, Muhammad Zaeem, et al.
Publicado: (2018)

Diagnostic and Therapeutic Potential of Extracellular Vesicles in B-Cell Malignancies
por: Gargiulo, Ernesto, et al.
Publicado: (2020)

Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
por: Gargiulo, Ernesto, et al.
Publicado: (2023)

Hijacker of the Antitumor Immune Response: Autophagy Is Showing Its Worst Facet
por: Viry, Elodie, et al.
Publicado: (2016)

Extracellular vesicles as potential tools for regenerative therapy
por: Rodriguez-Navarro, Jose Antonio, et al.
Publicado: (2020)

Evasion before invasion: Pre-cancer immunosurveillance
por: Angelova, Mihaela, et al.
Publicado: (2021)

The multifaceted role of autophagy in tumor evasion from immune surveillance
por: Janji, Bassam, et al.
Publicado: (2016)

A “vicious cycle” of NK-cell immune evasion in acute myeloid leukemia mediated by RANKL?
por: Schmiedel, Benjamin Joachim, et al.
Publicado: (2013)

The Critical Role of the Tumor Microenvironment in Shaping Natural Killer Cell-Mediated Anti-Tumor Immunity
por: Baginska, Joanna, et al.
Publicado: (2013)

The protective role of the microenvironment in hairy cell leukemia treatment: Facts and perspectives
por: Gargiulo, Ernesto, et al.
Publicado: (2023)

P598: DISRUPTION IN ONE-CARBON METABOLISM THROUGH MTHFD1 INHIBITION AS NOVEL THERAPEUTIC STRATEGY IN CHRONIC LYMPHOCYTIC LEUKEMIA
por: Viry, Elodie, et al.
Publicado: (2023)

Involvement of STAT3 in immune evasion during lung tumorigenesis
por: Kida, Hiroshi, et al.
Publicado: (2013)

Extracellular vesicles released by ovarian carcinoma contain arginase 1 that mitigates antitumor immune response
por: Sosnowska, Anna, et al.
Publicado: (2019)

A novel facet of tumor suppression by p53: Induction of tumor immunogenicity
por: Li, Hai, et al.
Publicado: (2012)

The Tumor Microenvironment-Dependent Transcription Factors AHR and HIF-1α Are Dispensable for Leukemogenesis in the Eµ-TCL1 Mouse Model of Chronic Lymphocytic Leukemia
por: Gonder, Susanne, et al.
Publicado: (2021)

Method for the Analysis of the Tumor Microenvironment by Mass Cytometry: Application to Chronic Lymphocytic Leukemia
por: Gonder, Susanne, et al.
Publicado: (2020)

Targeting mRNA translation aberrations: A novel approach for therapy in chronic lymphocytic leukemia
por: Klapp, Vanessa, et al.
Publicado: (2023)

Chronic activation of DNA damage signals causes tumor immune evasion in the chemoresistant niche
por: Jinushi, Masahisa
Publicado: (2012)

Oxysterols recruit tumor-supporting neutrophils within the tumor microenvironment: The many facets of tumor-derived oxysterols
por: Raccosta, Laura, et al.
Publicado: (2013)

Linking oncogenesis and immune system evasion in acquired resistance to EGFR-targeting antibodies: Lessons from a preclinical model
por: Garrido, Greta, et al.
Publicado: (2013)

Immune-mediated tumor evolution: Nanog links the emergence of a stem like cancer cell state and immune evasion
por: Mao, Chih-Ping, et al.
Publicado: (2014)

Imaging collagen degradation in vivo highlights a key role for M2-polarized macrophages in extracellular matrix degradation
por: Madsen, Daniel H, et al.
Publicado: (2013)

Metastamir-mediated immune evasion: miR-10b downregulates the stress-induced molecule MICB, hence avoid recognition by NKG2D receptor
por: Tsukerman, Pinchas, et al.
Publicado: (2013)

Strategies for purging CD96(+) stem cells in vitro and in vivo: New avenues for autologous stem cell transplantation in acute myeloid leukemia
por: Staudinger, Matthias, et al.
Publicado: (2013)

Editorial: New Insights Into the Complexity of Tumor Immunology in B-Cell Malignancies: Prognostic and Predictive Biomarkers and Therapy
por: Moussay, Etienne, et al.
Publicado: (2022)

Editorial: New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Tumor Immunology and Immunotherapy
por: Seiffert, Martina, et al.
Publicado: (2022)

Editorial: New Insights Into the Complexity of Tumor Immunology in B-Cell Malignancies: Disease Biology and Signaling
por: Paggetti, Jérôme, et al.
Publicado: (2021)

Interferons in hematopoiesis and leukemia
por: Schürch, Christian M, et al.
Publicado: (2013)

Targeting cathepsin G in myeloid leukemia
por: Alatrash, Gheath
Publicado: (2013)

Anti-leukemia activity of human gamma delta T cells
por: Siegers, Gabrielle M.
Publicado: (2012)

Understanding anti-leukemia responses to donor lymphocyte infusion
por: Bachireddy, Pavan, et al.
Publicado: (2014)

Peripheral T-cell tolerance in hosts with acute myeloid leukemia
por: Chen, Xiufen, et al.
Publicado: (2013)

Acute myeloid leukemia therapeutics: CARs in the driver’s seat
por: Mardiros, Armen, et al.
Publicado: (2013)

Immunotherapy of acute myeloid leukemia based on γδ T cells
por: Gertner-Dardenne, Julie, et al.
Publicado: (2012)

A co-stimulatory trap set by myeloid leukemia cells
por: Esendagli, Gunes
Publicado: (2013)

Transcriptomic profile of intrinsically chemoresistant acute myeloid leukemia patients
por: Horibata, Sachi
Publicado: (2019)

Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix
por: Salmon, Hélène, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_7511g9587lejejo0s02f46d208