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Microfluidic affinity selection of active SARS-CoV-2 virus particles

We report a microfluidic assay to select active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral particles (VPs), which were defined as intact particles with an accessible angiotensin-converting enzyme 2 receptor binding domain (RBD) on the spike (S) protein, from clinical samples....

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Detalles Bibliográficos
Autores principales: Gamage, Sachindra S. T., Pahattuge, Thilanga N., Wijerathne, Harshani, Childers, Katie, Vaidyanathan, Swarnagowri, Athapattu, Uditha S., Zhang, Lulu, Zhao, Zheng, Hupert, Mateusz L., Muller, Rolf M., Muller-Cohn, Judy, Dickerson, Janet, Dufek, Dylan, Geisbrecht, Brian V., Pathak, Harsh, Pessetto, Ziyan, Gan, Gregory N., Choi, Junseo, Park, Sunggook, Godwin, Andrew K., Witek, Malgorzata A., Soper, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519043/
https://www.ncbi.nlm.nih.gov/pubmed/36170362
http://dx.doi.org/10.1126/sciadv.abn9665

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