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LKB1 suppression promotes cardiomyocyte regeneration via LKB1-AMPK-YAP axis

The regenerative potential of cardiomyocytes in adult mammals is limited. The previous studies reported that cardiomyocyte proliferation is suppressed by AMP-activated protein kinase (AMPK). The role of liver kinase B1 (LKB1), as the major upstream kinase for AMPK, on cardiomyocyte proliferation is...

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Detalles Bibliográficos
Autores principales: Qu, Shuang, Liao, Qiao, Yu, Cheng, Chen, Yue, Luo, Hao, Xia, Xuewei, He, Duofen, Xu, Zaicheng, Jose, Pedro A., Li, Zhuxin, Wang, Wei Eric, Lyu, Qing Rex, Zeng, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519156/
https://www.ncbi.nlm.nih.gov/pubmed/35490365
http://dx.doi.org/10.17305/bjbms.2021.7225