FcγRIV is required for IgG2c mediated enhancement of RBC alloimmunization

Passive immunization with anti-D can prevent maternal alloimmunization to RhD thereby preventing hemolytic disease of the fetus and newborn. Unexpectedly, anti-D fails in some cases and some monoclonal anti-D preparations paradoxically enhances alloimmunization. The underlying mechanisms modulating...

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Detalles Bibliográficos
Autores principales: Qiu, Annie, Miller, Anabel, Zotti, Flavia Dei, Santhanakrishnan, Manjula, Hendrickson, Jeanne E., Tredicine, Maria, Stowell, Sean R., Luckey, Chance John, Zimring, James C., Hudson, Krystalyn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519184/
https://www.ncbi.nlm.nih.gov/pubmed/36189253
http://dx.doi.org/10.3389/fimmu.2022.972723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519184/
https://www.ncbi.nlm.nih.gov/pubmed/36189253
http://dx.doi.org/10.3389/fimmu.2022.972723

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