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FcγRIV is required for IgG2c mediated enhancement of RBC alloimmunization
Passive immunization with anti-D can prevent maternal alloimmunization to RhD thereby preventing hemolytic disease of the fetus and newborn. Unexpectedly, anti-D fails in some cases and some monoclonal anti-D preparations paradoxically enhances alloimmunization. The underlying mechanisms modulating...
Autores principales: | Qiu, Annie, Miller, Anabel, Zotti, Flavia Dei, Santhanakrishnan, Manjula, Hendrickson, Jeanne E., Tredicine, Maria, Stowell, Sean R., Luckey, Chance John, Zimring, James C., Hudson, Krystalyn E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519184/ https://www.ncbi.nlm.nih.gov/pubmed/36189253 http://dx.doi.org/10.3389/fimmu.2022.972723 |
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