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A bacterial pan-genome makes gene essentiality strain-dependent and evolvable
Many bacterial species are represented by a pan-genome, whose genetic repertoire far outstrips that of any single bacterial genome. Here we investigate how a bacterial pan-genome might influence gene essentiality and whether essential genes that are initially critical for the survival of an organism...
Autores principales: | Rosconi, Federico, Rudmann, Emily, Li, Jien, Surujon, Defne, Anthony, Jon, Frank, Matthew, Jones, Dakota S., Rock, Charles, Rosch, Jason W., Johnston, Christopher D., van Opijnen, Tim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519441/ https://www.ncbi.nlm.nih.gov/pubmed/36097170 http://dx.doi.org/10.1038/s41564-022-01208-7 |
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