Integrating microarray-based spatial transcriptomics and single-cell RNA-sequencing reveals tissue architecture in esophageal squamous cell carcinoma

BACKGROUND: The tumor microenvironment (TME) serves as an important factor in tumorigenesis and metastasis. Although distinct cell subsets can be identified via single-cell RNA sequencing (scRNA-seq), the spatial composition of cells within the TME is difficult to characterise. METHODS: Tissue sampl...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Zhou, Bolun, Yang, Zhenlin, Liu, Xiang, Huai, Qilin, Guo, Lei, Xue, Xuemin, Tan, Fengwei, Li, Yin, Xue, Qi, Gao, Shugeng, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519476/
https://www.ncbi.nlm.nih.gov/pubmed/36162205
http://dx.doi.org/10.1016/j.ebiom.2022.104281

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