Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration

The hostile microenvironment of the retina in patients with age-related macular degeneration (AMD) may trigger epithelial-to-mesenchymal transition (EMT) of grafted retinal pigment epithelial (RPE) cells, thus attenuating the therapeutic outcome. Here, we transformed human dedifferentiated induced p...

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Detalles Bibliográficos
Autores principales: Tian, Haibin, Chen, Zhiyang, Zhu, Xiaoman, Ou, Qingjian, Wang, Zhe, Wu, Binxin, Xu, Jing-Ying, Jin, Caixia, Gao, Furong, Wang, Juan, Zhang, Jingfa, Zhang, Jieping, Lu, Lixia, Xu, Guo-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519511/
https://www.ncbi.nlm.nih.gov/pubmed/36185374
http://dx.doi.org/10.1016/j.isci.2022.105050

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