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Activation of the human insulin receptor by non-insulin-related peptides

The human insulin receptor signalling system plays a critical role in glucose homeostasis. Insulin binding brings about extensive conformational change in the receptor extracellular region that in turn effects trans-activation of the intracellular tyrosine kinase domains and downstream signalling. O...

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Detalles Bibliográficos
Autores principales:	Kirk, Nicholas S., Chen, Qi, Wu, Yingzhe Ginger, Asante, Anastasia L., Hu, Haitao, Espinosa, Juan F., Martínez-Olid, Francisco, Margetts, Mai B., Mohammed, Faiz A., Kiselyov, Vladislav V., Barrett, David G., Lawrence, Michael C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519552/ https://www.ncbi.nlm.nih.gov/pubmed/36171189 http://dx.doi.org/10.1038/s41467-022-33315-8

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