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Mdm1 ablation results in retinal degeneration by specific intraflagellar transport defects of photoreceptor cells
Mouse double minute 1 (Mdm1) might be involved in the function and structure of centrioles and age-related retinal degeneration. However, the mechanism by which Mdm1 deficiency causes retinal degeneration remains unknown. We confirmed that the Mdm1 protein is localized at the connecting cilium (CC)...
Autores principales: | Son, Youlim, Kim, Soo-Jin, Kim, Hwa-Young, Lee, Junyeop, Kim, Jae-Ryong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519634/ https://www.ncbi.nlm.nih.gov/pubmed/36171205 http://dx.doi.org/10.1038/s41419-022-05237-2 |
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