TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis

Fatty liver is a highly heterogenous condition driven by various pathogenic factors in addition to the severity of steatosis. Protein insufficiency has been causally linked to fatty liver with incompletely defined mechanisms. Here we report that fatty liver is a sulfur amino acid insufficient state...

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Detalles Bibliográficos
Autores principales: Matye, David, Gunewardena, Sumedha, Chen, Jianglei, Wang, Huaiwen, Wang, Yifeng, Hasan, Mohammad Nazmul, Gu, Lijie, Clayton, Yung Dai, Du, Yanhong, Chen, Cheng, Friedman, Jacob E., Lu, Shelly C., Ding, Wen-Xing, Li, Tiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519740/
https://www.ncbi.nlm.nih.gov/pubmed/36171419
http://dx.doi.org/10.1038/s41467-022-33465-9

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