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Upregulation of an estrogen receptor-regulated gene by first generation progestins requires both the progesterone receptor and estrogen receptor alpha

Progestins, synthetic compounds designed to mimic the activity of natural progesterone (P(4)), are used globally in menopausal hormone therapy. Although the older progestins medroxyprogesterone acetate (MPA) and norethisterone (NET) have been implicated in increased breast cancer risk, little is kno...

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Detalles Bibliográficos
Autores principales:	Perkins, Meghan S., Louw-du Toit, Renate, Jackson, Hayley, Simons, Mishkah, Africander, Donita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519895/ https://www.ncbi.nlm.nih.gov/pubmed/36187129 http://dx.doi.org/10.3389/fendo.2022.959396

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