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The alternative splicing of intersectin 1 regulated by PTBP1 promotes human glioma progression

Intersectin 1 (ITSN1) contains two isoforms: ITSN1-S and ITSN1-L, which are highly regulated by alternative splicing. Our previous results showed that the two isoforms of ITSN1 displayed opposite functions: ITSN1-S promoted glioma development, while ITSN1-L exerted an inhibitory role in glioma progr...

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Detalles Bibliográficos
Autores principales: Lan, Chungen, Zhang, Huikun, Wang, Kezhen, Liu, Xiaoli, Zhao, Yawen, Guo, Zhifang, Zhang, Ning, Zhou, Yongxia, Gao, Manzhi, Gu, Feng, Ma, Yongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519902/
https://www.ncbi.nlm.nih.gov/pubmed/36171198
http://dx.doi.org/10.1038/s41419-022-05238-1