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The alternative splicing of intersectin 1 regulated by PTBP1 promotes human glioma progression
Intersectin 1 (ITSN1) contains two isoforms: ITSN1-S and ITSN1-L, which are highly regulated by alternative splicing. Our previous results showed that the two isoforms of ITSN1 displayed opposite functions: ITSN1-S promoted glioma development, while ITSN1-L exerted an inhibitory role in glioma progr...
Autores principales: | Lan, Chungen, Zhang, Huikun, Wang, Kezhen, Liu, Xiaoli, Zhao, Yawen, Guo, Zhifang, Zhang, Ning, Zhou, Yongxia, Gao, Manzhi, Gu, Feng, Ma, Yongjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519902/ https://www.ncbi.nlm.nih.gov/pubmed/36171198 http://dx.doi.org/10.1038/s41419-022-05238-1 |
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