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Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells
Androgen receptor variant 7 (AR-V7) is an important biomarker to guide treatment options for castration-resistant prostate cancer (CRPC) patients. Its detectability in circulating tumour cells (CTCs) opens non-invasive diagnostic avenues. While detectable at the transcript level, AR-V7 protein detec...
Autores principales: | Khan, Tanzila, Lock, John G., Ma, Yafeng, Harman, David G., de Souza, Paul, Chua, Wei, Balakrishnar, Bavanthi, Scott, Kieran F., Becker, Therese M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519917/ https://www.ncbi.nlm.nih.gov/pubmed/36171234 http://dx.doi.org/10.1038/s41598-022-20079-w |
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