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Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells

Androgen receptor variant 7 (AR-V7) is an important biomarker to guide treatment options for castration-resistant prostate cancer (CRPC) patients. Its detectability in circulating tumour cells (CTCs) opens non-invasive diagnostic avenues. While detectable at the transcript level, AR-V7 protein detec...

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Detalles Bibliográficos
Autores principales: Khan, Tanzila, Lock, John G., Ma, Yafeng, Harman, David G., de Souza, Paul, Chua, Wei, Balakrishnar, Bavanthi, Scott, Kieran F., Becker, Therese M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519917/
https://www.ncbi.nlm.nih.gov/pubmed/36171234
http://dx.doi.org/10.1038/s41598-022-20079-w

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