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A functional interaction between liprin-α1 and B56γ regulatory subunit of protein phosphatase 2A supports tumor cell motility
Scaffold liprin-α1 is required to assemble dynamic plasma membrane-associated platforms (PMAPs) at the front of migrating breast cancer cells, to promote protrusion and invasion. We show that the N-terminal region of liprin-α1 contains an LxxIxE motif interacting with B56 regulatory subunits of seri...
Autores principales: | Ripamonti, Marta, Lamarca, Andrea, Davey, Norman E., Tonoli, Diletta, Surini, Sara, de Curtis, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519923/ https://www.ncbi.nlm.nih.gov/pubmed/36171301 http://dx.doi.org/10.1038/s42003-022-03989-3 |
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