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Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice

Neural progenitor cells (NPC) represent potential cell transplantation therapies for CNS injuries. To understand how lesion environments influence transplanted NPC fate in vivo, we derived NPC expressing a ribosomal protein-hemagglutinin tag (RiboTag) for transcriptional profiling of transplanted NP...

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Detalles Bibliográficos
Autores principales: O’Shea, T. M., Ao, Y., Wang, S., Wollenberg, A. L., Kim, J. H., Ramos Espinoza, R. A., Czechanski, A., Reinholdt, L. G., Deming, T. J., Sofroniew, M. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519954/
https://www.ncbi.nlm.nih.gov/pubmed/36171203
http://dx.doi.org/10.1038/s41467-022-33382-x