Measurement of oxygen consumption rates of human renal proximal tubule cells in an array of organ-on-chip devices to monitor drug-induced metabolic shifts

Measurement of cell metabolism in moderate-throughput to high-throughput organ-on-chip (OOC) systems would expand the range of data collected for studying drug effects or disease in physiologically relevant tissue models. However, current measurement approaches rely on fluorescent imaging or colorim...

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Detalles Bibliográficos
Autores principales: Kann, Samuel H., Shaughnessey, Erin M., Coppeta, Jonathan R., Azizgolshani, Hesham, Isenberg, Brett C., Vedula, Else M., Zhang, Xin, Charest, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519964/
https://www.ncbi.nlm.nih.gov/pubmed/36187891
http://dx.doi.org/10.1038/s41378-022-00442-7

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