Cargando…

Involvement of endothelins in neuroprotection of valosin-containing protein modulators against retinal ganglion cell damage

We have previously shown that Kyoto University Substances (KUSs), valosin-containing protein (VCP) modulators, suppress cell death in retinal ganglion cells of glaucoma mouse models through alterations of various genes expressions. In this study, among the genes whose expression in retinal ganglion...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kusaka, Mami, Hasegawa, Tomoko, Ikeda, Hanako Ohashi, Inoue, Yumi, Iwai, Sachiko, Iida, Kei, Tsujikawa, Akitaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519977/ https://www.ncbi.nlm.nih.gov/pubmed/36171250 http://dx.doi.org/10.1038/s41598-022-20497-w

Ejemplares similares

Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model
por: Hasegawa, Tomoko, et al.
Publicado: (2020)

Hop flower extracts mitigate retinal ganglion cell degeneration in a glaucoma mouse model
por: Hasegawa, Tomoko, et al.
Publicado: (2020)

Branched Chain Amino Acids Promote ATP Production Via Translocation of Glucose Transporters
por: Iwai, Sachiko, et al.
Publicado: (2022)

Retinal ganglion cell protection by hop-flower extract as a novel neuroprotective strategy for glaucoma
por: Hasegawa, Tomoko, et al.
Publicado: (2021)

Long-term efficacy and safety of anti-VEGF therapy in retinitis pigmentosa: a case report
por: Miyata, Manabu, et al.
Publicado: (2018)

Adenosine triphosphate maintenance by branched chain amino acids as a novel neuroprotective strategy for retinal neurodegenerative diseases
por: Hasegawa, Tomoko, et al.
Publicado: (2019)

Wavelength of light and photophobia in inherited retinal dystrophy
por: Otsuka, Yuki, et al.
Publicado: (2020)

Detection Sensitivity of Retinitis Pigmentosa Progression Using Static Perimetry and Optical Coherence Tomography
por: Hasegawa, Tomoko, et al.
Publicado: (2021)

Expansion of retinal nerve fiber bundle narrowing in glaucoma: An adaptive optics scanning laser ophthalmoscopy study
por: Hasegawa, Tomoko, et al.
Publicado: (2020)

Relationship between Ocular Deviation and Visual Function in Retinitis Pigmentosa
por: Miyata, Manabu, et al.
Publicado: (2018)

Modulation of valosin-containing protein by Kyoto University Substances (KUS) as a novel therapeutic strategy for ischemic neuronal diseases
por: Hata, Masayuki, et al.
Publicado: (2017)

Clinical Characteristics, Differential Diagnosis and Genetic Analysis of Concentric Retinitis Pigmentosa
por: Nakahara, Mei, et al.
Publicado: (2021)

Neuroprotective effects of VCP modulators in mouse models of glaucoma
por: Nakano, Noriko, et al.
Publicado: (2016)

EYS is a major gene involved in retinitis pigmentosa in Japan: genetic landscapes revealed by stepwise genetic screening
por: Numa, Shogo, et al.
Publicado: (2020)

Nationwide incidence of central retinal artery occlusion in Japan: an exploratory descriptive study using the National Database of Health Insurance Claims (2011–2015)
por: Kido, Ai, et al.
Publicado: (2020)

Branched chain amino acids attenuate major pathologies in mouse models of retinal degeneration and glaucoma
por: Hasegawa, Tomoko, et al.
Publicado: (2018)

Safety and effectiveness of a novel neuroprotectant, KUS121, in patients with non-arteritic central retinal artery occlusion: An open-label, non-randomized, first-in-humans, phase 1/2 trial
por: Ikeda, Hanako Ohashi, et al.
Publicado: (2020)

Evaluation of Structure-Function Relationships in Longitudinal Changes of Glaucoma using the Spectralis OCT Follow-Up Mode
por: Suda, Kenji, et al.
Publicado: (2018)

Influence of Trabeculectomy with Mitomycin C on Longitudinal Changes in the Visual Field in Glaucoma Patients with High Myopia
por: Yamagata, Yutaro, et al.
Publicado: (2023)

KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats
por: Iwai, Sachiko, et al.
Publicado: (2021)

Longitudinal changes in complete avascular area assessed using anterior segmental optical coherence tomography angiography in filtering trabeculectomy bleb
por: Kido, Ai, et al.
Publicado: (2021)

Vascular derived endothelin receptor A controls endothelin-induced retinal ganglion cell death
por: Marola, Olivia J., et al.
Publicado: (2022)

Longitudinal changes in superficial microvasculature in glaucomatous retinal nerve fiber layer defects after disc hemorrhage
por: Okamoto, Yoko, et al.
Publicado: (2020)

KUS121, a VCP modulator, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress
por: Hata, Masayuki, et al.
Publicado: (2017)

Estimating the rate of retinal ganglion cell loss to detect glaucoma progression: An observational cohort study
por: Hirooka, Kazuyuki, et al.
Publicado: (2016)

KUS121, an ATP regulator, mitigates chorioretinal pathologies in animal models of age-related macular degeneration
por: Muraoka, Yuki, et al.
Publicado: (2018)

Reduction of lipid accumulation rescues Bietti’s crystalline dystrophy phenotypes
por: Hata, Masayuki, et al.
Publicado: (2018)

Endothelin 1-induced retinal ganglion cell death is largely mediated by JUN activation
por: Marola, Olivia J., et al.
Publicado: (2020)

Branch Retinal Vein Occlusion: Treatment Outcomes According to the Retinal Nonperfusion Area, Clinical Subtype, and Crossing Pattern
por: Iida-Miwa, Yuko, et al.
Publicado: (2019)

Endothelin B Receptors Contribute to Retinal Ganglion Cell Loss in a Rat Model of Glaucoma
por: Minton, Alena Z., et al.
Publicado: (2012)

Retinal Blood Flow Velocity Change in Parafoveal Capillary after Topical Tafluprost Treatment in Eyes with Primary Open-angle Glaucoma
por: Iida, Yuto, et al.
Publicado: (2017)

Taurine Provides Neuroprotection against Retinal Ganglion Cell Degeneration
por: Froger, Nicolas, et al.
Publicado: (2012)

p58(IPK) Is an Endogenous Neuroprotectant for Retinal Ganglion Cells
por: McLaughlin, Todd, et al.
Publicado: (2018)

Brimonidine is Neuroprotective in Animal Paradigm of Retinal Ganglion Cell Damage
por: Conti, Federica, et al.
Publicado: (2021)

Effect of smoking on macular function and retinal structure in retinitis pigmentosa
por: Oishi, Akio, et al.
Publicado: (2020)

Long-Term Effects on Retinal Structure and Function in a Mouse Endothelin-1 Model of Retinal Ganglion Cell Degeneration
por: Lakshmanan, Yamunadevi, et al.
Publicado: (2023)

Pilot study assessing the structural changes in posttrabecular aqueous humor outflow pathway after trabecular meshwork surgery using swept-source optical coherence tomography
por: Yoshikawa, Munemitsu, et al.
Publicado: (2018)

Changes in the deep vasculature assessed using anterior segment OCT angiography following trabecular meshwork targeted minimally invasive glaucoma surgery
por: Okamoto, Yoko, et al.
Publicado: (2022)

Neuoroprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration
por: Hasegawa, Tomoko, et al.
Publicado: (2016)

Endothelin-1 Mediated Decrease in Mitochondrial Gene Expression and Bioenergetics Contribute to Neurodegeneration of Retinal Ganglion Cells
por: Chaphalkar, Renuka M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bon8eju9hpebhofg6a26smjkth