Cargando…
Targeting cellular senescence in metabolic disease
Cellular senescence is a cell fate involving cell cycle arrest, resistance against apoptosis, and the development of a secretome that can be pro-inflammatory. In aging and obesity, senescent cells accumulate in many tissues, including adipose tissue, brain, kidney, pancreas, and liver. These senesce...
Autores principales: | Palmer, Allyson K., Tchkonia, Tamar, Kirkland, James L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520013/ https://www.ncbi.nlm.nih.gov/pubmed/36116755 http://dx.doi.org/10.1016/j.molmet.2022.101601 |
Ejemplares similares
-
Cellular Senescence: A Translational Perspective
por: Kirkland, James L., et al.
Publicado: (2017) -
Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity
por: Palmer, Allyson K., et al.
Publicado: (2015) -
Cellular senescence: at the nexus between ageing and diabetes
por: Palmer, Allyson K., et al.
Publicado: (2019) -
Senolytics: Potential for Alleviating Diabetes and Its Complications
por: Palmer, Allyson K, et al.
Publicado: (2021) -
COVID-19 and cellular senescence
por: Schmitt, Clemens A., et al.
Publicado: (2022)