Alkaline-sensitive two-pore domain potassium channels form functional heteromers in pancreatic β-cells

Two-pore domain K(+) channels (K(2P) channels), active as dimers, produce inhibitory currents regulated by a variety of stimuli. Among them, TWIK1-related alkalinization-activated K(+) channel 1 (TALK1), TWIK1-related alkalinization-activated K(+) channel 2 (TALK2), and TWIK1-related acid-sensitive...

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Detalles Bibliográficos
Autores principales: Khoubza, Lamyaa, Gilbert, Nicolas, Kim, Eun-Jin, Chatelain, Franck C., Feliciangeli, Sylvain, Abelanet, Sophie, Kang, Dawon, Lesage, Florian, Bichet, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520024/
https://www.ncbi.nlm.nih.gov/pubmed/36063992
http://dx.doi.org/10.1016/j.jbc.2022.102447

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