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ER entry pathway and glycosylation of GPI-anchored proteins are determined by N-terminal signal sequence and C-terminal GPI-attachment sequence

Newly synthesized proteins in the secretory pathway, including glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs), need to be correctly targeted and imported into the endoplasmic reticulum (ER) lumen. GPI-APs are synthesized in the cytosol as preproproteins, which contain an N-terminal s...

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Detalles Bibliográficos
Autores principales:	Hirata, Tetsuya, Yang, Jing, Tomida, Seita, Tokoro, Yuko, Kinoshita, Taroh, Fujita, Morihisa, Kizuka, Yasuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520029/ https://www.ncbi.nlm.nih.gov/pubmed/36055406 http://dx.doi.org/10.1016/j.jbc.2022.102444

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