The methyl-CpG-binding domain 2 facilitates pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation

Although DNA methylation has been recognised in the pathogenesis of idiopathic pulmonary fibrosis (IPF), the exact mechanisms are yet to be fully addressed. Herein, we demonstrate that lungs originated from IPF patients and mice after bleomycin (BLM)-induced pulmonary fibrosis are characterised by a...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Zhang, Lei, Huang, Teng, Wu, Guo-Rao, Zhou, Qing, Wang, Fa-Xi, Chen, Long-Min, Sun, Fei, Lv, Yongman, Xiong, Fei, Zhang, Shu, Yu, Qilin, Yang, Ping, Gu, Weikuan, Xu, Yongjian, Zhao, Jianping, Zhang, Huilan, Xiong, Weining, Wang, Cong-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520034/
https://www.ncbi.nlm.nih.gov/pubmed/35086828
http://dx.doi.org/10.1183/13993003.03697-2020

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