Cargando…

Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein

Owing to the crucial role of Src in cancer metastasis, interruption of Src and its signaling has been considered a promising strategy for cancer metastasis treatment. Cucurbitacin B, a dietary triterpenoid, has been shown to possess anti-proliferative and apoptosis-inducing activities in cholangioca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaewmeesri, Putthaporn, Pocasap, Piman, Kukongviriyapan, Veerapol, Prawan, Auemduan, Kongpetch, Sarinya, Senggunprai, Laddawan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520142/ https://www.ncbi.nlm.nih.gov/pubmed/36154723 http://dx.doi.org/10.1177/15347354221124861

Ejemplares similares

13-cis-retinoic acid inhibits the self-renewal, migration, invasion and adhesion of cholangiocarcinoma cells
por: Butsri, Siriwoot, et al.
Publicado: (2023)

Licochalcone A Induces Cholangiocarcinoma Cell Death Via Suppression of Nrf2 and NF-κB Signaling Pathways
por: Laphanuwat, Phatthamon, et al.
Publicado: (2022)

Crucial Role of Heme Oxygenase-1 on the Sensitivity of Cholangiocarcinoma Cells to Chemotherapeutic Agents
por: Kongpetch, Sarinya, et al.
Publicado: (2012)

All-trans-retinoic acid induces RARB-dependent apoptosis via ROS induction and enhances cisplatin sensitivity by NRF2 downregulation in cholangiocarcinoma cells
por: Butsri, Siriwoot, et al.
Publicado: (2022)

Inhibition of growth and migration of cholangiocarcinoma cells by pamidronate
por: Buranrat, Benjaporn, et al.
Publicado: (2019)

Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells
por: Tusskorn, Ornanong, et al.
Publicado: (2013)

The Inhibition Kinetics and Potential Anti-Migration Activity of NQO1 Inhibitory Coumarins on Cholangiocarcinoma Cells
por: Khunluck, Tueanjai, et al.
Publicado: (2018)

Suppression of NAD(P)H-quinone oxidoreductase 1 enhanced the susceptibility of cholangiocarcinoma cells to chemotherapeutic agents
por: Zeekpudsa, Ponsilp, et al.
Publicado: (2014)

Association of arterial stiffness with single nucleotide polymorphism rs1333049 and metabolic risk factors
por: Phababpha, Suphawadee, et al.
Publicado: (2013)

Alyssin and Iberin in Cruciferous Vegetables Exert Anticancer Activity in HepG2 by Increasing Intracellular Reactive Oxygen Species and Tubulin Depolymerization
por: Pocasap, Piman, et al.
Publicado: (2019)

Chemopreventive Effect of Cratoxylum formosum (Jack) ssp. pruniflorum on Initial Stage Hepatocarcinogenesis in Rats
por: Pocasap, Piman, et al.
Publicado: (2021)

Thai Rat-Tailed Radish Prevents Hepatocarcinogenesis in Rats by Blocking Mutagenicity, Inducing Hepatic Phase II Enzyme, and Decreasing Hepatic Pro-Inflammatory Cytokine Gene Expression
por: Pocasap, Piman, et al.
Publicado: (2023)

Lack of Targetable FGFR2 Fusions in Endemic Fluke-Associated Cholangiocarcinoma
por: Kongpetch, Sarinya, et al.
Publicado: (2020)

Therapeutic targeting of ARID1A and PI3K/AKT pathway alterations in cholangiocarcinoma
por: Tessiri, Supharada, et al.
Publicado: (2022)

Diagnostic and Prognostic Value of Circulating Cell-Free DNA for Cholangiocarcinoma
por: Wintachai, Preawwalee, et al.
Publicado: (2021)

Cucurbitacins – An insight into medicinal leads from nature
por: Kaushik, Ujjwal, et al.
Publicado: (2015)

Tyrosine–Chlorambucil Conjugates Facilitate Cellular Uptake through L-Type Amino Acid Transporter 1 (LAT1) in Human Breast Cancer Cell Line MCF-7
por: Pocasap, Piman, et al.
Publicado: (2020)

The Effect of the EGFR - Targeting Compound 3-[(4-Phenylpyrimidin-2-yl) Amino] Benzene-1-Sulfonamide (13f) against Cholangiocarcinoma Cell Lines
por: Samatiwat, Papavee, et al.
Publicado: (2021)

Curcumin Protects against Cadmium-Induced Vascular Dysfunction, Hypertension and Tissue Cadmium Accumulation in Mice
por: Kukongviriyapan, Upa, et al.
Publicado: (2014)

Asiatic Acid Alleviates Hemodynamic and Metabolic Alterations via Restoring eNOS/iNOS Expression, Oxidative Stress, and Inflammation in Diet-Induced Metabolic Syndrome Rats
por: Pakdeechote, Poungrat, et al.
Publicado: (2014)

Rice Bran Protein Hydrolysates Improve Insulin Resistance and Decrease Pro-inflammatory Cytokine Gene Expression in Rats Fed a High Carbohydrate-High Fat Diet
por: Boonloh, Kampeebhorn, et al.
Publicado: (2015)

Peptides-Derived from Thai Rice Bran Improves Endothelial Function in 2K-1C Renovascular Hypertensive Rats
por: Boonla, Orachorn, et al.
Publicado: (2015)

Protective Effects of Streblus asper Leaf Extract on H(2)O(2)-Induced ROS in SK-N-SH Cells and MPTP-Induced Parkinson's Disease-Like Symptoms in C57BL/6 Mouse
por: Singsai, Kanathip, et al.
Publicado: (2015)

Pluchea indica Leaf Extract Alleviates Dyslipidemia and Hepatic Steatosis by Modifying the Expression of Lipid Metabolism-Related Genes in Rats Fed a High Fat-High Fructose Diet
por: Singdam, Patcharin, et al.
Publicado: (2022)

Asiatic acid attenuates renin-angiotensin system activation and improves vascular function in high-carbohydrate, high-fat diet fed rats
por: Maneesai, Putcharawipa, et al.
Publicado: (2016)

Mamao Pomace Extract Alleviates Hypertension and Oxidative Stress in Nitric Oxide Deficient Rats
por: Kukongviriyapan, Upa, et al.
Publicado: (2015)

Tetrahydrocurcumin Protects against Cadmium-Induced Hypertension, Raised Arterial Stiffness and Vascular Remodeling in Mice
por: Sangartit, Weerapon, et al.
Publicado: (2014)

Cucurbitacins: elucidation of their interactions with the cytoskeleton
por: Wang, Xiaojuan, et al.
Publicado: (2017)

Pharmacokinetics and Biological Activity of Cucurbitacins
por: Delgado-Tiburcio, Eugenia Elisa, et al.
Publicado: (2022)

Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in l-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT(1)R Expression
por: Maneesai, Putcharawipa, et al.
Publicado: (2016)

Hesperidin Prevents Nitric Oxide Deficiency-Induced Cardiovascular Remodeling in Rats via Suppressing TGF-β1 and MMPs Protein Expression
por: Maneesai, Putcharawipa, et al.
Publicado: (2018)

Knecorticosanones C–H from the fruits of Knema globularia (Lam.) warb
por: Chuenban, Chindawadee, et al.
Publicado: (2021)

Ferulic Acid Alleviates Changes in a Rat Model of Metabolic Syndrome Induced by High-Carbohydrate, High-Fat Diet
por: Senaphan, Ketmanee, et al.
Publicado: (2015)

Ellagic Acid Prevents L-NAME-Induced Hypertension via Restoration of eNOS and p47(phox) Expression in Rats
por: Berkban, Thewarid, et al.
Publicado: (2015)

An updated review of Cucurbitacins and their biological and pharmacological activities
por: Chung, Sun Ok, et al.
Publicado: (2015)

Recent Advances in the Application of Cucurbitacins as Anticancer Agents
por: Zieniuk, Bartłomiej, et al.
Publicado: (2023)

Cucurbitacin D exhibits potent anti-cancer activity in cervical cancer
por: Sikander, Mohammed, et al.
Publicado: (2016)

Synthesis of Cucurbitacin B Derivatives as Potential Anti-Hepatocellular Carcinoma Agents
por: Ge, Weizhi, et al.
Publicado: (2018)

In Vitro and In Vivo Antitumor Activity of Cucurbitacin C, a Novel Natural Product From Cucumber
por: Wu, Dinglan, et al.
Publicado: (2019)

Cucurbitacins from the Leaves of Citrullus colocynthis (L.) Schrad
por: Chawech, Rachid, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_p36ejp0mfkpp4r5n34vn3utvi0