Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease

Proprotein convertase subtilisin/kexins (PCSKs) constitute a family of nine related proteases: PCSK1-7, MBTPS1, and PCSK9. Apart from PCSK9, little is known about PCSKs in cardiovascular disease. Here, we aimed to investigate the expression landscape and druggability potential of the entire PCSK fam...

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Detalles Bibliográficos
Autores principales: Suur, Bianca E., Chemaly, Melody, Lindquist Liljeqvist, Moritz, Djordjevic, Djordje, Stenemo, Markus, Bergman, Otto, Karlöf, Eva, Lengquist, Mariette, Odeberg, Jacob, Hurt-Camejo, Eva, Eriksson, Per, Ketelhuth, Daniel F.J., Roy, Joy, Hedin, Ulf, Nyberg, Michael, Matic, Ljubica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520287/
https://www.ncbi.nlm.nih.gov/pubmed/36188622
http://dx.doi.org/10.3389/fphar.2022.988561

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