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Non-infectious complications following transrectal prostate needle biopsy – Outcomes from over 8000 procedures
BACKGROUND: Prostate needle biopsy (PNB) remains the referent standard for diagnosing prostate cancer. Contemporary data highlight an increase in PNB-related infections particularly when performed transrectally. Non-infectious complications, however, may similarly contribute to biopsy-related morbid...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Asian Pacific Prostate Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520411/ https://www.ncbi.nlm.nih.gov/pubmed/36225283 http://dx.doi.org/10.1016/j.prnil.2022.04.002 |
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author | Sosenko, Adrian Owens, Russell G. Yang, Ae Lim Alzubaidi, Ahmad Guzzo, Thomas Trabulsi, Edouard Danella, John Diorio, Gregory Reese, Adam Tomaszewski, Jeffrey Ginzburg, Serge Smaldone, Marc Fonshell, Claudette Syed, Kaynaat Jacobs, Bruce Singer, Eric A. Raman, Jay D. |
author_facet | Sosenko, Adrian Owens, Russell G. Yang, Ae Lim Alzubaidi, Ahmad Guzzo, Thomas Trabulsi, Edouard Danella, John Diorio, Gregory Reese, Adam Tomaszewski, Jeffrey Ginzburg, Serge Smaldone, Marc Fonshell, Claudette Syed, Kaynaat Jacobs, Bruce Singer, Eric A. Raman, Jay D. |
author_sort | Sosenko, Adrian |
collection | PubMed |
description | BACKGROUND: Prostate needle biopsy (PNB) remains the referent standard for diagnosing prostate cancer. Contemporary data highlight an increase in PNB-related infections particularly when performed transrectally. Non-infectious complications, however, may similarly contribute to biopsy-related morbidity. We review the incidence and predictors of non-infectious complications following transrectal PNB in a large statewide quality registry. METHODS: Transrectal ultrasound-guided prostate needle biopsies performed between 2015 and 2018 were retrospectively reviewed. The incidence and distribution of non-infectious complications were annotated. Clinical, demographic, and biopsy variables of interest were evaluated by logistic regression for potential association with specific types of non-infectious complications. RESULTS: Of 8,102 biopsies, 277 (3.4%) biopsies had reported post-procedure complications including 199 (2.5%) non-infectious and 78 (0.9%) infectious. Among the non-infectious complications, the most common events included urinary or rectal bleeding (74; 0.9%), urinary retention (70, 0.9%), vasovagal syncope (13, 0.2%), and severe post-operative pain (10, 0.1%). Approximately 56% of these non-infectious complications required an Emergency Department visit (111/199) and 27% (54/199) hospital admission for monitoring. Increasing transrectal ultrasound prostate volume was associated with post-procedure urinary retention (Odds ratio (OR) 1.07, 1.02–1.11, p = 0.002). No specific variables noted association with post-biopsy bleeding. CONCLUSION: Non-infectious complications occurred 2.5 times more often than infectious complications following transrectal ultrasound prostate needle biopsies. Larger prostate size was associated with a greater risk of post-procedure urinary retention. These data originating from experience from over 100 urologists across different health systems provide an important framework in counseling patients regarding expectations following transrectal prostate biopsy. |
format | Online Article Text |
id | pubmed-9520411 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Asian Pacific Prostate Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-95204112022-10-11 Non-infectious complications following transrectal prostate needle biopsy – Outcomes from over 8000 procedures Sosenko, Adrian Owens, Russell G. Yang, Ae Lim Alzubaidi, Ahmad Guzzo, Thomas Trabulsi, Edouard Danella, John Diorio, Gregory Reese, Adam Tomaszewski, Jeffrey Ginzburg, Serge Smaldone, Marc Fonshell, Claudette Syed, Kaynaat Jacobs, Bruce Singer, Eric A. Raman, Jay D. Prostate Int Original Article BACKGROUND: Prostate needle biopsy (PNB) remains the referent standard for diagnosing prostate cancer. Contemporary data highlight an increase in PNB-related infections particularly when performed transrectally. Non-infectious complications, however, may similarly contribute to biopsy-related morbidity. We review the incidence and predictors of non-infectious complications following transrectal PNB in a large statewide quality registry. METHODS: Transrectal ultrasound-guided prostate needle biopsies performed between 2015 and 2018 were retrospectively reviewed. The incidence and distribution of non-infectious complications were annotated. Clinical, demographic, and biopsy variables of interest were evaluated by logistic regression for potential association with specific types of non-infectious complications. RESULTS: Of 8,102 biopsies, 277 (3.4%) biopsies had reported post-procedure complications including 199 (2.5%) non-infectious and 78 (0.9%) infectious. Among the non-infectious complications, the most common events included urinary or rectal bleeding (74; 0.9%), urinary retention (70, 0.9%), vasovagal syncope (13, 0.2%), and severe post-operative pain (10, 0.1%). Approximately 56% of these non-infectious complications required an Emergency Department visit (111/199) and 27% (54/199) hospital admission for monitoring. Increasing transrectal ultrasound prostate volume was associated with post-procedure urinary retention (Odds ratio (OR) 1.07, 1.02–1.11, p = 0.002). No specific variables noted association with post-biopsy bleeding. CONCLUSION: Non-infectious complications occurred 2.5 times more often than infectious complications following transrectal ultrasound prostate needle biopsies. Larger prostate size was associated with a greater risk of post-procedure urinary retention. These data originating from experience from over 100 urologists across different health systems provide an important framework in counseling patients regarding expectations following transrectal prostate biopsy. Asian Pacific Prostate Society 2022-09 2022-04-23 /pmc/articles/PMC9520411/ /pubmed/36225283 http://dx.doi.org/10.1016/j.prnil.2022.04.002 Text en © 2022 Asian Pacific Prostate Society. Publishing services by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Sosenko, Adrian Owens, Russell G. Yang, Ae Lim Alzubaidi, Ahmad Guzzo, Thomas Trabulsi, Edouard Danella, John Diorio, Gregory Reese, Adam Tomaszewski, Jeffrey Ginzburg, Serge Smaldone, Marc Fonshell, Claudette Syed, Kaynaat Jacobs, Bruce Singer, Eric A. Raman, Jay D. Non-infectious complications following transrectal prostate needle biopsy – Outcomes from over 8000 procedures |
title | Non-infectious complications following transrectal prostate needle biopsy – Outcomes from over 8000 procedures |
title_full | Non-infectious complications following transrectal prostate needle biopsy – Outcomes from over 8000 procedures |
title_fullStr | Non-infectious complications following transrectal prostate needle biopsy – Outcomes from over 8000 procedures |
title_full_unstemmed | Non-infectious complications following transrectal prostate needle biopsy – Outcomes from over 8000 procedures |
title_short | Non-infectious complications following transrectal prostate needle biopsy – Outcomes from over 8000 procedures |
title_sort | non-infectious complications following transrectal prostate needle biopsy – outcomes from over 8000 procedures |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520411/ https://www.ncbi.nlm.nih.gov/pubmed/36225283 http://dx.doi.org/10.1016/j.prnil.2022.04.002 |
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