A Facile Synthetic Method for Anhydride from Carboxylic Acid with the Promotion of Triphenylphosphine Oxide and Oxaloyl Chloride

[Image: see text] A highly efficient synthesis reaction of carboxylic anhydrides catalyzed by triphenylphosphine oxide is described for the quick synthesis of a range of symmetric carboxylic anhydrides and cyclic anhydrides under mild and neutral conditions with a high yield. The system adopts the s...

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Autores principales: Lu, Mengyu, Fan, Huihui, Liu, Qing, Sun, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520564/
https://www.ncbi.nlm.nih.gov/pubmed/36188305
http://dx.doi.org/10.1021/acsomega.2c03991
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author Lu, Mengyu
Fan, Huihui
Liu, Qing
Sun, Xiaoling
author_facet Lu, Mengyu
Fan, Huihui
Liu, Qing
Sun, Xiaoling
author_sort Lu, Mengyu
collection PubMed
description [Image: see text] A highly efficient synthesis reaction of carboxylic anhydrides catalyzed by triphenylphosphine oxide is described for the quick synthesis of a range of symmetric carboxylic anhydrides and cyclic anhydrides under mild and neutral conditions with a high yield. The system adopts the strong reactive intermediate Ph(3)PCl(2) as the catalyst of carboxylic acid salt; driven by catalytic reaction, the synthesis takes a relatively short time to complete.
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spelling pubmed-95205642022-09-30 A Facile Synthetic Method for Anhydride from Carboxylic Acid with the Promotion of Triphenylphosphine Oxide and Oxaloyl Chloride Lu, Mengyu Fan, Huihui Liu, Qing Sun, Xiaoling ACS Omega [Image: see text] A highly efficient synthesis reaction of carboxylic anhydrides catalyzed by triphenylphosphine oxide is described for the quick synthesis of a range of symmetric carboxylic anhydrides and cyclic anhydrides under mild and neutral conditions with a high yield. The system adopts the strong reactive intermediate Ph(3)PCl(2) as the catalyst of carboxylic acid salt; driven by catalytic reaction, the synthesis takes a relatively short time to complete. American Chemical Society 2022-09-13 /pmc/articles/PMC9520564/ /pubmed/36188305 http://dx.doi.org/10.1021/acsomega.2c03991 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Lu, Mengyu
Fan, Huihui
Liu, Qing
Sun, Xiaoling
A Facile Synthetic Method for Anhydride from Carboxylic Acid with the Promotion of Triphenylphosphine Oxide and Oxaloyl Chloride
title A Facile Synthetic Method for Anhydride from Carboxylic Acid with the Promotion of Triphenylphosphine Oxide and Oxaloyl Chloride
title_full A Facile Synthetic Method for Anhydride from Carboxylic Acid with the Promotion of Triphenylphosphine Oxide and Oxaloyl Chloride
title_fullStr A Facile Synthetic Method for Anhydride from Carboxylic Acid with the Promotion of Triphenylphosphine Oxide and Oxaloyl Chloride
title_full_unstemmed A Facile Synthetic Method for Anhydride from Carboxylic Acid with the Promotion of Triphenylphosphine Oxide and Oxaloyl Chloride
title_short A Facile Synthetic Method for Anhydride from Carboxylic Acid with the Promotion of Triphenylphosphine Oxide and Oxaloyl Chloride
title_sort facile synthetic method for anhydride from carboxylic acid with the promotion of triphenylphosphine oxide and oxaloyl chloride
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520564/
https://www.ncbi.nlm.nih.gov/pubmed/36188305
http://dx.doi.org/10.1021/acsomega.2c03991
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